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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAPZA1 All Species: 43.33
Human Site: T182 Identified Species: 59.58
UniProt: P52907 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52907 NP_006126.1 286 32923 T182 S E W K F T I T P P T A Q V V
Chimpanzee Pan troglodytes XP_513632 286 32891 T182 S E W K F T I T P P T A Q V V
Rhesus Macaque Macaca mulatta XP_001107677 286 32932 T182 S E W K F T I T P P T A Q V V
Dog Lupus familis XP_533066 286 32966 T182 S E W K F T I T P P T A Q V V
Cat Felis silvestris
Mouse Mus musculus P47753 286 32921 T182 S E W K F T I T P P S A Q V V
Rat Rattus norvegicus B2GUZ5 286 32891 T182 S E W K F T I T P P T A Q V V
Wallaby Macropus eugenll A4D7S9 286 32928 T182 S E W K F T I T P S T T Q V V
Platypus Ornith. anatinus Q07E00 286 32980 T182 S E W K F T I T P S T T Q V V
Chicken Gallus gallus P13127 286 32941 T182 S E W K F T I T P P T A Q V A
Frog Xenopus laevis P25229 256 29408 S154 W K F T I S G S T A Q L V G V
Zebra Danio Brachydanio rerio XP_689117 286 32709 S182 S E W K F N I S Q S S A Q V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W2N0 286 32741 Q180 S Q W H V T F Q A G S G T A E
Honey Bee Apis mellifera XP_624862 288 32841 S184 W T V S F S P S S G N A E L R
Nematode Worm Caenorhab. elegans P34685 282 32163 S180 V P V G D G K S G S Q E M K G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82631 308 35020 S187 P Q N F C N G S W R S V W N I
Baker's Yeast Sacchar. cerevisiae P28495 268 30681 H162 P N N F W N G H W R S S Y I Y
Red Bread Mold Neurospora crassa Q9P5K9 269 29610 L161 W N G R W R S L Y I Y D P S N
Conservation
Percent
Protein Identity: 100 96.8 99.6 97.1 N.A. 96.5 97.1 86 84.9 92.3 78.6 81.4 N.A. 63.2 64.2 55.5 N.A.
Protein Similarity: 100 97.1 99.6 98.9 N.A. 98.9 99.3 94 94 96.1 85.3 90.9 N.A. 76.2 77.7 69.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 93.3 100 86.6 86.6 93.3 6.6 66.6 N.A. 20 13.3 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 86.6 86.6 93.3 33.3 80 N.A. 33.3 40 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28.9 32.1 35.6
Protein Similarity: N.A. N.A. N.A. 50 52.4 58
P-Site Identity: N.A. N.A. N.A. 0 0 0
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 6 6 0 53 0 6 6 % A
% Cys: 0 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 6 0 0 0 0 0 0 6 0 0 0 % D
% Glu: 0 59 0 0 0 0 0 0 0 0 0 6 6 0 6 % E
% Phe: 0 0 6 12 65 0 6 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 6 6 0 6 18 0 6 12 0 6 0 6 6 % G
% His: 0 0 0 6 0 0 0 6 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 6 0 59 0 0 6 0 0 0 6 6 % I
% Lys: 0 6 0 59 0 0 6 0 0 0 0 0 0 6 0 % K
% Leu: 0 0 0 0 0 0 0 6 0 0 0 6 0 6 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % M
% Asn: 0 12 12 0 0 18 0 0 0 0 6 0 0 6 6 % N
% Pro: 12 6 0 0 0 0 6 0 53 42 0 0 6 0 0 % P
% Gln: 0 12 0 0 0 0 0 6 6 0 12 0 59 0 0 % Q
% Arg: 0 0 0 6 0 6 0 0 0 12 0 0 0 0 6 % R
% Ser: 65 0 0 6 0 12 6 30 6 24 30 6 0 6 0 % S
% Thr: 0 6 0 6 0 59 0 53 6 0 48 12 6 0 0 % T
% Val: 6 0 12 0 6 0 0 0 0 0 0 6 6 59 59 % V
% Trp: 18 0 65 0 12 0 0 0 12 0 0 0 6 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 6 0 6 0 6 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _