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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPZA1
All Species:
34.55
Human Site:
T217
Identified Species:
47.5
UniProt:
P52907
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52907
NP_006126.1
286
32923
T217
K
D
V
Q
D
S
L
T
V
S
N
E
A
Q
T
Chimpanzee
Pan troglodytes
XP_513632
286
32891
T217
K
D
V
Q
D
S
L
T
V
S
N
E
A
Q
T
Rhesus Macaque
Macaca mulatta
XP_001107677
286
32932
T217
K
D
V
Q
D
S
L
T
V
S
N
E
A
Q
T
Dog
Lupus familis
XP_533066
286
32966
T217
K
D
V
Q
D
S
V
T
V
S
N
E
V
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
P47753
286
32921
T217
K
D
V
Q
D
S
V
T
V
S
N
E
V
Q
T
Rat
Rattus norvegicus
B2GUZ5
286
32891
T217
K
D
V
Q
D
S
V
T
V
S
N
E
V
Q
T
Wallaby
Macropus eugenll
A4D7S9
286
32928
T217
K
D
I
Q
E
S
L
T
V
S
N
E
V
Q
T
Platypus
Ornith. anatinus
Q07E00
286
32980
T217
K
D
I
Q
D
S
L
T
V
S
N
E
V
Q
T
Chicken
Gallus gallus
P13127
286
32941
Q217
K
D
I
Q
D
S
V
Q
V
S
S
D
V
Q
T
Frog
Xenopus laevis
P25229
256
29408
S189
V
Q
E
S
I
T
I
S
G
E
A
Q
T
A
K
Zebra Danio
Brachydanio rerio
XP_689117
286
32709
V217
K
E
V
E
E
S
I
V
V
T
N
E
V
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2N0
286
32741
S215
S
S
K
E
C
R
E
S
V
V
V
S
N
E
Q
Honey Bee
Apis mellifera
XP_624862
288
32841
P219
K
E
V
K
E
S
L
P
I
S
S
E
K
Q
T
Nematode Worm
Caenorhab. elegans
P34685
282
32163
V215
E
P
V
L
K
V
N
V
S
A
D
F
D
K
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82631
308
35020
E222
Y
F
E
E
G
N
V
E
L
D
A
K
K
D
F
Baker's Yeast
Sacchar. cerevisiae
P28495
268
30681
G197
G
N
V
S
F
Q
S
G
K
D
I
N
Q
S
N
Red Bread Mold
Neurospora crassa
Q9P5K9
269
29610
T196
L
L
T
N
K
T
V
T
A
T
V
S
S
G
T
Conservation
Percent
Protein Identity:
100
96.8
99.6
97.1
N.A.
96.5
97.1
86
84.9
92.3
78.6
81.4
N.A.
63.2
64.2
55.5
N.A.
Protein Similarity:
100
97.1
99.6
98.9
N.A.
98.9
99.3
94
94
96.1
85.3
90.9
N.A.
76.2
77.7
69.5
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
80
86.6
60
0
53.3
N.A.
6.6
53.3
13.3
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
93.3
93.3
86.6
26.6
86.6
N.A.
26.6
86.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.9
32.1
35.6
Protein Similarity:
N.A.
N.A.
N.A.
50
52.4
58
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
6
6
12
0
18
6
0
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
53
0
0
48
0
0
0
0
12
6
6
6
6
0
% D
% Glu:
6
12
12
18
18
0
6
6
0
6
0
59
0
6
0
% E
% Phe:
0
6
0
0
6
0
0
0
0
0
0
6
0
0
6
% F
% Gly:
6
0
0
0
6
0
0
6
6
0
0
0
0
6
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
18
0
6
0
12
0
6
0
6
0
0
0
0
% I
% Lys:
65
0
6
6
12
0
0
0
6
0
0
6
12
6
6
% K
% Leu:
6
6
0
6
0
0
36
0
6
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
6
0
6
6
0
0
0
53
6
6
0
6
% N
% Pro:
0
6
0
0
0
0
0
6
0
0
0
0
0
0
0
% P
% Gln:
0
6
0
53
0
6
0
6
0
0
0
6
6
65
6
% Q
% Arg:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% R
% Ser:
6
6
0
12
0
65
6
12
6
59
12
12
6
6
0
% S
% Thr:
0
0
6
0
0
12
0
53
0
12
0
0
6
0
77
% T
% Val:
6
0
59
0
0
6
36
12
65
6
12
0
42
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _