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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAPZA1 All Species: 55.15
Human Site: T265 Identified Species: 75.83
UniProt: P52907 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52907 NP_006126.1 286 32923 T265 L R R Q L P V T R T K I D W N
Chimpanzee Pan troglodytes XP_513632 286 32891 T265 L R R Q L P V T R T K I D W N
Rhesus Macaque Macaca mulatta XP_001107677 286 32932 T265 L R R Q L P V T R T K I D W N
Dog Lupus familis XP_533066 286 32966 T265 L R R Q L P V T R T K I D W N
Cat Felis silvestris
Mouse Mus musculus P47753 286 32921 T265 L R R Q L P V T R T K I D W N
Rat Rattus norvegicus B2GUZ5 286 32891 T265 L R R Q L P V T R T K I D W N
Wallaby Macropus eugenll A4D7S9 286 32928 T265 L R R Q L P V T R T K I D W N
Platypus Ornith. anatinus Q07E00 286 32980 T265 L R R Q L P V T R T K I D W N
Chicken Gallus gallus P13127 286 32941 T265 L R R Q L P V T R T K I D W N
Frog Xenopus laevis P25229 256 29408 T237 R Q L P V T R T K I D W N K I
Zebra Danio Brachydanio rerio XP_689117 286 32709 T265 L R R Q L P V T R T K I D W N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W2N0 286 32741 P263 K A M R R Q L P I T R T K I D
Honey Bee Apis mellifera XP_624862 288 32841 M267 L R R Q L P V M R T K I D W N
Nematode Worm Caenorhab. elegans P34685 282 32163 T263 L R R Q L P V T R A K M D W N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O82631 308 35020 N270 A Y S K L P D N T F K D L R R
Baker's Yeast Sacchar. cerevisiae P28495 268 30681 T245 L R R R L P V T R S K I N W G
Red Bread Mold Neurospora crassa Q9P5K9 269 29610 T244 L R R Q L P V T R Q K I E W D
Conservation
Percent
Protein Identity: 100 96.8 99.6 97.1 N.A. 96.5 97.1 86 84.9 92.3 78.6 81.4 N.A. 63.2 64.2 55.5 N.A.
Protein Similarity: 100 97.1 99.6 98.9 N.A. 98.9 99.3 94 94 96.1 85.3 90.9 N.A. 76.2 77.7 69.5 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 100 100 100 6.6 100 N.A. 6.6 93.3 86.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 100 100 100 33.3 100 N.A. 33.3 93.3 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28.9 32.1 35.6
Protein Similarity: N.A. N.A. N.A. 50 52.4 58
P-Site Identity: N.A. N.A. N.A. 20 73.3 80
P-Site Similarity: N.A. N.A. N.A. 26.6 93.3 93.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 6 0 0 0 0 0 0 0 6 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 6 0 0 0 6 6 71 0 12 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 6 6 0 77 0 6 6 % I
% Lys: 6 0 0 6 0 0 0 0 6 0 89 0 6 6 0 % K
% Leu: 83 0 6 0 89 0 6 0 0 0 0 0 6 0 0 % L
% Met: 0 0 6 0 0 0 0 6 0 0 0 6 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 6 0 0 0 0 12 0 71 % N
% Pro: 0 0 0 6 0 89 0 6 0 0 0 0 0 0 0 % P
% Gln: 0 6 0 77 0 6 0 0 0 6 0 0 0 0 0 % Q
% Arg: 6 83 83 12 6 0 6 0 83 0 6 0 0 6 6 % R
% Ser: 0 0 6 0 0 0 0 0 0 6 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 6 0 83 6 71 0 6 0 0 0 % T
% Val: 0 0 0 0 6 0 83 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 6 0 83 0 % W
% Tyr: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _