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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPZA1
All Species:
45.45
Human Site:
Y199
Identified Species:
62.5
UniProt:
P52907
Number Species:
16
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52907
NP_006126.1
286
32923
Y199
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
L
Chimpanzee
Pan troglodytes
XP_513632
286
32891
Y199
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
L
Rhesus Macaque
Macaca mulatta
XP_001107677
286
32932
Y199
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
L
Dog
Lupus familis
XP_533066
286
32966
Y199
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
P47753
286
32921
Y199
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
L
Rat
Rattus norvegicus
B2GUZ5
286
32891
Y199
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
L
Wallaby
Macropus eugenll
A4D7S9
286
32928
Y199
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
L
Platypus
Ornith. anatinus
Q07E00
286
32980
Y199
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
L
Chicken
Gallus gallus
P13127
286
32941
Y199
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
L
Frog
Xenopus laevis
P25229
256
29408
D171
I
Q
V
H
Y
Y
E
D
G
N
V
Q
L
V
S
Zebra Danio
Brachydanio rerio
XP_689117
286
32709
Y199
L
K
I
Q
V
H
Y
Y
E
D
G
N
V
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2N0
286
32741
H197
G
V
L
K
V
Q
V
H
Y
Y
E
D
G
N
V
Honey Bee
Apis mellifera
XP_624862
288
32841
Y201
L
K
V
Q
V
H
Y
Y
E
D
G
N
V
Q
L
Nematode Worm
Caenorhab. elegans
P34685
282
32163
E197
L
S
Q
V
H
Y
Y
E
D
G
N
V
Q
L
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82631
308
35020
D204
Q
D
E
S
Q
V
L
D
I
K
G
K
L
Q
V
Baker's Yeast
Sacchar. cerevisiae
P28495
268
30681
Q179
E
T
R
E
L
S
G
Q
I
S
T
Q
V
H
Y
Red Bread Mold
Neurospora crassa
Q9P5K9
269
29610
D178
I
E
G
S
I
K
V
D
V
H
Y
Y
E
D
G
Conservation
Percent
Protein Identity:
100
96.8
99.6
97.1
N.A.
96.5
97.1
86
84.9
92.3
78.6
81.4
N.A.
63.2
64.2
55.5
N.A.
Protein Similarity:
100
97.1
99.6
98.9
N.A.
98.9
99.3
94
94
96.1
85.3
90.9
N.A.
76.2
77.7
69.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
100
100
100
0
100
N.A.
6.6
93.3
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
100
100
100
40
100
N.A.
40
100
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.9
32.1
35.6
Protein Similarity:
N.A.
N.A.
N.A.
50
52.4
58
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
0
0
0
0
0
18
6
65
0
6
0
6
0
% D
% Glu:
6
6
6
6
0
0
6
6
65
0
6
0
6
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% F
% Gly:
6
0
6
0
0
0
6
0
6
6
71
0
6
0
6
% G
% His:
0
0
0
6
6
65
0
6
0
6
0
0
0
6
0
% H
% Ile:
12
0
59
0
6
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
65
0
6
0
6
0
0
0
6
0
6
0
0
0
% K
% Leu:
71
0
6
0
6
0
6
0
0
0
0
0
12
6
65
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
6
6
65
0
6
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
6
6
6
65
6
6
0
6
0
0
0
12
6
71
0
% Q
% Arg:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
6
0
12
0
6
0
0
0
6
0
0
0
0
6
% S
% Thr:
0
6
0
0
0
0
0
0
0
0
6
0
0
0
0
% T
% Val:
0
6
12
6
71
6
12
0
6
0
6
6
71
6
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
6
12
71
65
6
6
6
6
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _