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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP5C
All Species:
18.18
Human Site:
S105
Identified Species:
25
UniProt:
P53041
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53041
NP_006238.1
499
56879
S105
G
Y
Y
R
R
A
A
S
N
M
A
L
G
K
F
Chimpanzee
Pan troglodytes
XP_512768
499
56846
S105
G
Y
Y
R
R
A
A
S
N
M
A
L
G
K
F
Rhesus Macaque
Macaca mulatta
XP_001111749
499
56900
S105
G
Y
Y
R
R
A
A
S
N
M
A
L
G
K
F
Dog
Lupus familis
XP_855029
473
53972
K98
R
D
Y
E
T
V
V
K
V
K
P
H
D
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q60676
499
56828
S105
G
Y
Y
R
R
A
A
S
N
M
A
L
G
K
F
Rat
Rattus norvegicus
P53042
499
56898
S105
G
Y
Y
R
R
A
A
S
N
M
A
L
G
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48463
309
35545
Frog
Xenopus laevis
Q6IP91
307
35104
Zebra Danio
Brachydanio rerio
A9JRC7
307
35078
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23696
309
35450
Honey Bee
Apis mellifera
XP_624242
489
56031
A96
G
Y
Y
R
R
A
A
A
H
M
S
L
G
K
F
Nematode Worm
Caenorhab. elegans
Q9XW79
333
37341
Sea Urchin
Strong. purpuratus
XP_796785
500
56974
A108
G
Y
Y
R
R
A
T
A
N
M
A
L
G
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150042
483
54661
F96
A
Y
L
A
M
G
K
F
K
E
A
L
K
D
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
C124
A
T
R
K
L
K
E
C
E
K
A
V
M
K
L
Baker's Yeast
Sacchar. cerevisiae
P53043
513
57976
A116
A
K
P
N
D
P
A
A
T
K
A
L
L
T
C
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
Conservation
Percent
Protein Identity:
100
99.8
99.4
91.5
N.A.
98
98
N.A.
N.A.
27.4
29
28.8
N.A.
26.8
63.7
30
64.6
Protein Similarity:
100
100
99.8
93.1
N.A.
99.1
99.4
N.A.
N.A.
40.4
40.2
40
N.A.
39.6
79.9
43
81.6
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
0
0
0
N.A.
0
80
0
80
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
0
0
0
N.A.
0
100
0
86.6
Percent
Protein Identity:
N.A.
55.1
N.A.
51.4
41.9
29.4
Protein Similarity:
N.A.
73.1
N.A.
69.7
59.8
42.6
P-Site Identity:
N.A.
26.6
N.A.
13.3
20
0
P-Site Similarity:
N.A.
26.6
N.A.
26.6
26.6
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
0
0
6
0
42
42
18
0
0
53
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
6
% C
% Asp:
0
6
0
0
6
0
0
0
0
0
0
0
6
6
6
% D
% Glu:
0
0
0
6
0
0
6
0
6
6
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
42
% F
% Gly:
42
0
0
0
0
6
0
0
0
0
0
0
42
0
0
% G
% His:
0
0
0
0
0
0
0
0
6
0
0
6
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% I
% Lys:
0
6
0
6
0
6
6
6
6
18
0
0
6
53
0
% K
% Leu:
0
0
6
0
6
0
0
0
0
0
0
53
6
0
6
% L
% Met:
0
0
0
0
6
0
0
0
0
42
0
0
6
0
0
% M
% Asn:
0
0
0
6
0
0
0
0
36
0
0
0
0
0
0
% N
% Pro:
0
0
6
0
0
6
0
0
0
0
6
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
6
0
6
42
42
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
30
0
0
6
0
0
0
0
% S
% Thr:
0
6
0
0
6
0
6
0
6
0
0
0
0
6
0
% T
% Val:
0
0
0
0
0
6
6
0
6
0
0
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
48
48
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _