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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP5C
All Species:
39.7
Human Site:
S277
Identified Species:
54.58
UniProt:
P53041
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53041
NP_006238.1
499
56879
S277
G
D
F
V
D
R
G
S
F
S
V
E
V
I
L
Chimpanzee
Pan troglodytes
XP_512768
499
56846
S277
G
D
F
V
D
R
G
S
F
S
V
E
V
I
L
Rhesus Macaque
Macaca mulatta
XP_001111749
499
56900
S277
G
D
F
V
D
R
G
S
F
S
V
E
V
I
L
Dog
Lupus familis
XP_855029
473
53972
F261
V
E
V
I
L
T
L
F
G
F
K
L
L
Y
P
Cat
Felis silvestris
Mouse
Mus musculus
Q60676
499
56828
S277
G
D
F
V
D
R
G
S
F
S
V
E
V
I
L
Rat
Rattus norvegicus
P53042
499
56898
S277
G
D
F
V
D
R
G
S
F
S
V
E
V
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48463
309
35545
L99
Y
S
V
E
T
V
T
L
L
V
A
L
K
V
R
Frog
Xenopus laevis
Q6IP91
307
35104
L97
S
V
E
T
F
L
L
L
L
A
L
K
V
R
Y
Zebra Danio
Brachydanio rerio
A9JRC7
307
35078
L97
S
V
E
T
F
L
L
L
L
A
L
K
V
R
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23696
309
35450
L99
Y
S
V
E
T
V
T
L
L
V
A
L
K
V
R
Honey Bee
Apis mellifera
XP_624242
489
56031
S268
G
D
F
V
D
R
G
S
F
S
V
E
C
I
F
Nematode Worm
Caenorhab. elegans
Q9XW79
333
37341
L123
V
E
T
F
L
L
L
L
A
L
K
A
R
Y
P
Sea Urchin
Strong. purpuratus
XP_796785
500
56974
S281
G
D
F
V
D
R
G
S
F
S
V
E
V
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150042
483
54661
S262
G
D
F
V
D
R
G
S
F
S
V
E
V
I
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
S317
G
D
F
V
D
R
G
S
F
S
V
E
I
I
L
Baker's Yeast
Sacchar. cerevisiae
P53043
513
57976
S284
G
D
F
V
D
R
G
S
W
S
C
E
V
A
L
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
K98
G
D
Y
V
D
R
G
K
Q
S
L
E
T
I
C
Conservation
Percent
Protein Identity:
100
99.8
99.4
91.5
N.A.
98
98
N.A.
N.A.
27.4
29
28.8
N.A.
26.8
63.7
30
64.6
Protein Similarity:
100
100
99.8
93.1
N.A.
99.1
99.4
N.A.
N.A.
40.4
40.2
40
N.A.
39.6
79.9
43
81.6
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
0
6.6
6.6
N.A.
0
86.6
0
100
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
6.6
26.6
26.6
N.A.
6.6
86.6
6.6
100
Percent
Protein Identity:
N.A.
55.1
N.A.
51.4
41.9
29.4
Protein Similarity:
N.A.
73.1
N.A.
69.7
59.8
42.6
P-Site Identity:
N.A.
100
N.A.
93.3
80
60
P-Site Similarity:
N.A.
100
N.A.
100
86.6
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
6
12
12
6
0
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
6
0
6
0
6
% C
% Asp:
0
65
0
0
65
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
12
12
12
0
0
0
0
0
0
0
65
0
0
0
% E
% Phe:
0
0
59
6
12
0
0
6
53
6
0
0
0
0
6
% F
% Gly:
65
0
0
0
0
0
65
0
6
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
6
0
0
0
0
0
0
0
0
6
59
0
% I
% Lys:
0
0
0
0
0
0
0
6
0
0
12
12
12
0
0
% K
% Leu:
0
0
0
0
12
18
24
30
24
6
18
18
6
0
53
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
65
0
0
0
0
0
0
6
12
12
% R
% Ser:
12
12
0
0
0
0
0
59
0
65
0
0
0
0
0
% S
% Thr:
0
0
6
12
12
6
12
0
0
0
0
0
6
0
0
% T
% Val:
12
12
18
65
0
12
0
0
0
12
53
0
59
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% W
% Tyr:
12
0
6
0
0
0
0
0
0
0
0
0
0
12
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _