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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP5C
All Species:
22.73
Human Site:
S396
Identified Species:
31.25
UniProt:
P53041
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53041
NP_006238.1
499
56879
S396
P
Q
P
Q
N
G
R
S
I
S
K
R
G
V
S
Chimpanzee
Pan troglodytes
XP_512768
499
56846
S396
P
Q
P
Q
N
G
R
S
V
S
K
R
G
V
S
Rhesus Macaque
Macaca mulatta
XP_001111749
499
56900
S396
P
Q
P
Q
N
G
R
S
V
S
K
R
G
V
S
Dog
Lupus familis
XP_855029
473
53972
S370
P
Q
P
Q
N
G
R
S
V
S
K
R
G
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60676
499
56828
S396
P
Q
P
Q
N
G
R
S
V
S
K
R
G
V
S
Rat
Rattus norvegicus
P53042
499
56898
S396
P
Q
P
Q
N
G
R
S
V
S
K
R
G
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48463
309
35545
G207
W
S
D
P
D
D
R
G
G
W
G
I
S
P
R
Frog
Xenopus laevis
Q6IP91
307
35104
G205
S
D
P
E
D
T
T
G
W
G
V
S
P
R
G
Zebra Danio
Brachydanio rerio
A9JRC7
307
35078
G205
S
D
P
E
D
T
T
G
W
G
V
S
P
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23696
309
35450
G207
W
S
D
P
D
D
R
G
G
W
G
I
S
P
R
Honey Bee
Apis mellifera
XP_624242
489
56031
A387
P
Q
P
Q
P
G
R
A
P
S
K
R
G
V
G
Nematode Worm
Caenorhab. elegans
Q9XW79
333
37341
G231
D
P
E
E
G
N
V
G
W
G
L
S
P
R
G
Sea Urchin
Strong. purpuratus
XP_796785
500
56974
P393
C
E
L
L
W
S
D
P
Q
P
R
P
G
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150042
483
54661
G381
P
Q
P
Q
L
G
R
G
P
S
K
R
G
V
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
G436
P
Q
P
L
P
G
R
G
P
S
K
R
G
V
G
Baker's Yeast
Sacchar. cerevisiae
P53043
513
57976
G403
P
Q
E
A
N
G
M
G
P
S
Q
R
G
L
G
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
W206
G
L
L
C
D
L
L
W
S
D
P
D
K
D
I
Conservation
Percent
Protein Identity:
100
99.8
99.4
91.5
N.A.
98
98
N.A.
N.A.
27.4
29
28.8
N.A.
26.8
63.7
30
64.6
Protein Similarity:
100
100
99.8
93.1
N.A.
99.1
99.4
N.A.
N.A.
40.4
40.2
40
N.A.
39.6
79.9
43
81.6
P-Site Identity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
6.6
6.6
N.A.
6.6
73.3
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
20
20
N.A.
13.3
80
6.6
26.6
Percent
Protein Identity:
N.A.
55.1
N.A.
51.4
41.9
29.4
Protein Similarity:
N.A.
73.1
N.A.
69.7
59.8
42.6
P-Site Identity:
N.A.
73.3
N.A.
66.6
46.6
0
P-Site Similarity:
N.A.
80
N.A.
66.6
60
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
6
0
0
0
6
0
0
0
0
0
0
6
% A
% Cys:
6
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
12
12
0
30
12
6
0
0
6
0
6
0
6
0
% D
% Glu:
0
6
12
18
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
6
0
0
0
6
59
0
48
12
18
12
0
65
0
36
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
6
0
0
12
0
0
6
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
53
0
6
0
0
% K
% Leu:
0
6
12
12
6
6
6
0
0
0
6
0
0
6
0
% L
% Met:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
42
6
0
0
0
0
0
0
0
0
0
% N
% Pro:
59
6
65
12
12
0
0
6
24
6
6
6
18
12
0
% P
% Gln:
0
59
0
48
0
0
0
0
6
0
6
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
65
0
0
0
6
59
0
24
12
% R
% Ser:
12
12
0
0
0
6
0
36
6
59
0
18
12
0
42
% S
% Thr:
0
0
0
0
0
12
12
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
6
0
30
0
12
0
0
53
0
% V
% Trp:
12
0
0
0
6
0
0
6
18
12
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _