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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP5C
All Species:
22.73
Human Site:
S460
Identified Species:
31.25
UniProt:
P53041
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53041
NP_006238.1
499
56879
S460
D
Q
M
G
N
K
A
S
Y
I
H
L
Q
G
S
Chimpanzee
Pan troglodytes
XP_512768
499
56846
S460
D
Q
M
G
N
K
A
S
Y
I
H
L
Q
G
S
Rhesus Macaque
Macaca mulatta
XP_001111749
499
56900
S460
D
Q
M
G
N
K
A
S
Y
I
H
L
Q
G
S
Dog
Lupus familis
XP_855029
473
53972
S434
D
Q
M
G
N
K
A
S
Y
I
H
L
R
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60676
499
56828
S460
D
Q
M
G
N
K
A
S
Y
I
H
L
Q
G
S
Rat
Rattus norvegicus
P53042
499
56898
S460
D
Q
M
G
N
K
A
S
Y
I
H
L
Q
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48463
309
35545
N271
N
Y
C
Y
R
C
G
N
Q
A
A
I
M
E
L
Frog
Xenopus laevis
Q6IP91
307
35104
V269
Y
C
Y
R
C
G
N
V
A
A
I
L
E
L
D
Zebra Danio
Brachydanio rerio
A9JRC7
307
35078
V269
Y
C
Y
R
C
G
N
V
A
A
I
L
E
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23696
309
35450
N271
N
Y
C
Y
R
C
G
N
Q
A
A
L
M
E
L
Honey Bee
Apis mellifera
XP_624242
489
56031
A451
D
T
M
G
N
R
G
A
F
I
T
L
N
G
K
Nematode Worm
Caenorhab. elegans
Q9XW79
333
37341
V295
Y
C
Y
R
C
G
N
V
A
A
I
L
E
L
D
Sea Urchin
Strong. purpuratus
XP_796785
500
56974
D457
F
S
A
P
N
Y
C
D
Q
I
G
N
K
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150042
483
54661
A445
D
Q
M
G
N
K
G
A
F
I
R
F
T
A
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
A500
D
Q
M
G
N
K
G
A
F
I
R
F
E
A
P
Baker's Yeast
Sacchar. cerevisiae
P53043
513
57976
G467
D
S
Q
G
N
L
G
G
V
I
H
V
V
P
G
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
P270
L
V
T
L
F
S
A
P
N
Y
C
G
E
F
D
Conservation
Percent
Protein Identity:
100
99.8
99.4
91.5
N.A.
98
98
N.A.
N.A.
27.4
29
28.8
N.A.
26.8
63.7
30
64.6
Protein Similarity:
100
100
99.8
93.1
N.A.
99.1
99.4
N.A.
N.A.
40.4
40.2
40
N.A.
39.6
79.9
43
81.6
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
0
6.6
6.6
N.A.
6.6
46.6
6.6
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
13.3
13.3
N.A.
20
66.6
13.3
33.3
Percent
Protein Identity:
N.A.
55.1
N.A.
51.4
41.9
29.4
Protein Similarity:
N.A.
73.1
N.A.
69.7
59.8
42.6
P-Site Identity:
N.A.
46.6
N.A.
46.6
33.3
6.6
P-Site Similarity:
N.A.
60
N.A.
66.6
40
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
0
0
0
42
18
18
30
12
0
0
12
6
% A
% Cys:
0
18
12
0
18
12
6
0
0
0
6
0
0
0
0
% C
% Asp:
59
0
0
0
0
0
0
6
0
0
0
0
0
0
24
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
30
12
0
% E
% Phe:
6
0
0
0
6
0
0
0
18
0
0
12
0
6
0
% F
% Gly:
0
0
0
59
0
18
36
6
0
0
6
6
0
48
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
42
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
65
18
6
0
0
0
% I
% Lys:
0
0
0
0
0
48
0
0
0
0
0
0
6
0
6
% K
% Leu:
6
0
0
6
0
6
0
0
0
0
0
65
0
18
12
% L
% Met:
0
0
53
0
0
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
12
0
0
0
65
0
18
12
6
0
0
6
6
0
0
% N
% Pro:
0
0
0
6
0
0
0
6
0
0
0
0
0
6
12
% P
% Gln:
0
48
6
0
0
0
0
0
18
0
0
0
30
0
0
% Q
% Arg:
0
0
0
18
12
6
0
0
0
0
12
0
6
0
0
% R
% Ser:
0
12
0
0
0
6
0
36
0
0
0
0
0
0
36
% S
% Thr:
0
6
6
0
0
0
0
0
0
0
6
0
6
0
0
% T
% Val:
0
6
0
0
0
0
0
18
6
0
0
6
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
18
12
18
12
0
6
0
0
36
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _