KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP5C
All Species:
40.3
Human Site:
Y266
Identified Species:
55.42
UniProt:
P53041
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53041
NP_006238.1
499
56879
Y266
L
P
S
E
T
N
P
Y
I
F
N
G
D
F
V
Chimpanzee
Pan troglodytes
XP_512768
499
56846
Y266
L
P
S
E
T
N
P
Y
I
F
N
G
D
F
V
Rhesus Macaque
Macaca mulatta
XP_001111749
499
56900
Y266
L
P
S
E
T
N
P
Y
I
F
N
G
D
F
V
Dog
Lupus familis
XP_855029
473
53972
G250
N
G
D
F
V
D
R
G
S
F
S
V
E
V
I
Cat
Felis silvestris
Mouse
Mus musculus
Q60676
499
56828
Y266
L
P
S
E
T
N
P
Y
I
F
N
G
D
F
V
Rat
Rattus norvegicus
P53042
499
56898
Y266
L
P
S
E
T
N
P
Y
I
F
N
G
D
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48463
309
35545
D88
L
F
M
G
D
Y
V
D
R
G
Y
Y
S
V
E
Frog
Xenopus laevis
Q6IP91
307
35104
R86
F
M
G
D
F
V
D
R
G
F
Y
S
V
E
T
Zebra Danio
Brachydanio rerio
A9JRC7
307
35078
R86
F
M
G
D
F
V
D
R
G
F
Y
S
V
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23696
309
35450
D88
L
F
M
G
D
Y
V
D
R
G
Y
Y
S
V
E
Honey Bee
Apis mellifera
XP_624242
489
56031
Y257
L
P
S
E
T
N
P
Y
L
F
N
G
D
F
V
Nematode Worm
Caenorhab. elegans
Q9XW79
333
37341
G112
L
G
D
F
V
D
R
G
F
Y
S
V
E
T
F
Sea Urchin
Strong. purpuratus
XP_796785
500
56974
Y270
L
P
S
E
D
N
P
Y
L
F
N
G
D
F
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150042
483
54661
Y251
L
P
S
E
E
N
P
Y
L
F
N
G
D
F
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
Y306
L
P
S
E
E
N
P
Y
L
F
N
G
D
F
V
Baker's Yeast
Sacchar. cerevisiae
P53043
513
57976
Y273
K
V
G
P
K
H
T
Y
L
F
N
G
D
F
V
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
Y87
G
F
P
P
E
A
N
Y
L
F
L
G
D
Y
V
Conservation
Percent
Protein Identity:
100
99.8
99.4
91.5
N.A.
98
98
N.A.
N.A.
27.4
29
28.8
N.A.
26.8
63.7
30
64.6
Protein Similarity:
100
100
99.8
93.1
N.A.
99.1
99.4
N.A.
N.A.
40.4
40.2
40
N.A.
39.6
79.9
43
81.6
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
6.6
6.6
6.6
N.A.
6.6
93.3
6.6
86.6
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
N.A.
6.6
13.3
13.3
N.A.
6.6
100
33.3
93.3
Percent
Protein Identity:
N.A.
55.1
N.A.
51.4
41.9
29.4
Protein Similarity:
N.A.
73.1
N.A.
69.7
59.8
42.6
P-Site Identity:
N.A.
86.6
N.A.
86.6
46.6
33.3
P-Site Similarity:
N.A.
93.3
N.A.
93.3
60
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
12
18
12
12
12
0
0
0
0
65
0
0
% D
% Glu:
0
0
0
53
18
0
0
0
0
0
0
0
12
12
12
% E
% Phe:
12
18
0
12
12
0
0
0
6
83
0
0
0
59
6
% F
% Gly:
6
12
18
12
0
0
0
12
12
12
0
65
0
0
0
% G
% His:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
6
% I
% Lys:
6
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
71
0
0
0
0
0
0
0
36
0
6
0
0
0
0
% L
% Met:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
0
0
53
6
0
0
0
59
0
0
0
0
% N
% Pro:
0
53
6
12
0
0
53
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
12
12
0
0
0
0
0
0
% R
% Ser:
0
0
53
0
0
0
0
0
6
0
12
12
12
0
0
% S
% Thr:
0
0
0
0
36
0
6
0
0
0
0
0
0
6
12
% T
% Val:
0
6
0
0
12
12
12
0
0
0
0
12
12
18
65
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
65
0
6
24
12
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _