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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP5C
All Species:
35.15
Human Site:
Y323
Identified Species:
48.33
UniProt:
P53041
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53041
NP_006238.1
499
56879
Y323
E
G
E
V
K
A
K
Y
T
A
Q
M
Y
E
L
Chimpanzee
Pan troglodytes
XP_512768
499
56846
Y323
E
G
E
V
K
A
K
Y
T
A
Q
M
Y
E
L
Rhesus Macaque
Macaca mulatta
XP_001111749
499
56900
Y323
E
G
E
V
K
A
K
Y
T
A
Q
M
Y
E
L
Dog
Lupus familis
XP_855029
473
53972
E307
Q
M
Y
E
L
F
S
E
V
F
E
W
L
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q60676
499
56828
Y323
E
G
E
V
K
A
K
Y
T
A
Q
M
Y
E
L
Rat
Rattus norvegicus
P53042
499
56898
Y323
E
G
E
V
K
A
K
Y
T
A
Q
M
Y
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48463
309
35545
Y145
G
N
A
N
V
W
K
Y
F
T
D
L
F
D
Y
Frog
Xenopus laevis
Q6IP91
307
35104
C143
S
V
T
V
W
R
Y
C
T
E
I
F
D
Y
L
Zebra Danio
Brachydanio rerio
A9JRC7
307
35078
C143
S
V
T
V
W
R
Y
C
T
E
I
F
D
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23696
309
35450
Y145
G
N
A
N
V
W
K
Y
F
T
D
L
F
D
Y
Honey Bee
Apis mellifera
XP_624242
489
56031
Y314
D
G
E
V
K
A
K
Y
S
A
Q
M
A
E
L
Nematode Worm
Caenorhab. elegans
Q9XW79
333
37341
T169
A
S
V
W
K
H
C
T
E
V
F
D
Y
L
S
Sea Urchin
Strong. purpuratus
XP_796785
500
56974
Y327
Y
G
E
V
R
S
K
Y
T
N
Q
M
A
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150042
483
54661
L308
E
G
E
V
R
S
K
L
G
E
K
F
V
E
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
L363
E
G
E
V
R
S
K
L
S
E
K
F
V
D
L
Baker's Yeast
Sacchar. cerevisiae
P53043
513
57976
Y330
E
D
E
C
K
Y
K
Y
S
Q
R
I
F
N
M
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
Y144
Y
D
E
C
K
R
R
Y
N
I
K
L
W
K
T
Conservation
Percent
Protein Identity:
100
99.8
99.4
91.5
N.A.
98
98
N.A.
N.A.
27.4
29
28.8
N.A.
26.8
63.7
30
64.6
Protein Similarity:
100
100
99.8
93.1
N.A.
99.1
99.4
N.A.
N.A.
40.4
40.2
40
N.A.
39.6
79.9
43
81.6
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
13.3
20
20
N.A.
13.3
80
13.3
60
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
33.3
20
20
N.A.
33.3
93.3
13.3
80
Percent
Protein Identity:
N.A.
55.1
N.A.
51.4
41.9
29.4
Protein Similarity:
N.A.
73.1
N.A.
69.7
59.8
42.6
P-Site Identity:
N.A.
46.6
N.A.
40
33.3
20
P-Site Similarity:
N.A.
66.6
N.A.
73.3
66.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
12
0
0
36
0
0
0
36
0
0
12
0
0
% A
% Cys:
0
0
0
12
0
0
6
12
0
0
0
0
0
0
0
% C
% Asp:
6
12
0
0
0
0
0
0
0
0
12
6
12
24
0
% D
% Glu:
48
0
65
6
0
0
0
6
6
24
6
0
0
42
0
% E
% Phe:
0
0
0
0
0
6
0
0
12
6
6
24
18
0
0
% F
% Gly:
12
53
0
0
0
0
0
0
6
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
6
12
6
0
0
0
% I
% Lys:
0
0
0
0
53
0
71
0
0
0
18
0
0
6
0
% K
% Leu:
0
0
0
0
6
0
0
12
0
0
0
18
6
6
71
% L
% Met:
0
6
0
0
0
0
0
0
0
0
0
42
0
0
6
% M
% Asn:
0
12
0
12
0
0
0
0
6
6
0
0
0
6
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% P
% Gln:
6
0
0
0
0
0
0
0
0
6
42
0
0
0
0
% Q
% Arg:
0
0
0
0
18
18
6
0
0
0
6
0
0
0
0
% R
% Ser:
12
6
0
0
0
18
6
0
18
0
0
0
0
0
6
% S
% Thr:
0
0
12
0
0
0
0
6
48
12
0
0
0
0
6
% T
% Val:
0
12
6
65
12
0
0
0
6
6
0
0
12
0
0
% V
% Trp:
0
0
0
6
12
12
0
0
0
0
0
6
6
0
0
% W
% Tyr:
12
0
6
0
0
6
12
65
0
0
0
0
36
12
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _