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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP5C
All Species:
26.06
Human Site:
Y422
Identified Species:
35.83
UniProt:
P53041
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53041
NP_006238.1
499
56879
Y422
L
E
E
N
N
L
D
Y
I
I
R
S
H
E
V
Chimpanzee
Pan troglodytes
XP_512768
499
56846
Y422
L
E
E
N
N
L
D
Y
I
I
R
S
H
E
V
Rhesus Macaque
Macaca mulatta
XP_001111749
499
56900
Y422
L
E
E
N
N
L
D
Y
I
I
R
S
H
E
V
Dog
Lupus familis
XP_855029
473
53972
Y396
L
E
E
N
H
L
D
Y
I
I
R
S
H
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q60676
499
56828
Y422
L
E
E
N
Q
L
D
Y
I
I
R
S
H
E
V
Rat
Rattus norvegicus
P53042
499
56898
Y422
L
E
E
N
Q
L
D
Y
I
I
R
S
H
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48463
309
35545
G233
E
T
F
N
H
A
N
G
L
T
L
V
S
R
A
Frog
Xenopus laevis
Q6IP91
307
35104
I231
Q
F
N
A
A
N
N
I
D
M
I
C
R
A
H
Zebra Danio
Brachydanio rerio
A9JRC7
307
35078
I231
Q
F
N
A
A
N
D
I
D
M
I
C
R
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23696
309
35450
G233
E
T
F
N
N
T
N
G
L
T
L
V
S
R
A
Honey Bee
Apis mellifera
XP_624242
489
56031
Y413
L
A
M
N
N
L
D
Y
I
V
R
S
H
E
V
Nematode Worm
Caenorhab. elegans
Q9XW79
333
37341
V257
T
F
C
E
T
N
G
V
D
L
I
C
R
A
H
Sea Urchin
Strong. purpuratus
XP_796785
500
56974
L419
P
D
V
T
K
K
F
L
E
H
N
N
L
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150042
483
54661
L407
L
Q
E
N
N
L
D
L
I
V
R
S
H
E
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
L462
L
Q
D
N
N
L
D
L
L
V
R
S
H
E
V
Baker's Yeast
Sacchar. cerevisiae
P53043
513
57976
K429
L
R
N
N
K
L
R
K
I
F
R
S
H
E
L
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
V232
F
T
F
G
P
D
V
V
S
R
F
L
Q
K
H
Conservation
Percent
Protein Identity:
100
99.8
99.4
91.5
N.A.
98
98
N.A.
N.A.
27.4
29
28.8
N.A.
26.8
63.7
30
64.6
Protein Similarity:
100
100
99.8
93.1
N.A.
99.1
99.4
N.A.
N.A.
40.4
40.2
40
N.A.
39.6
79.9
43
81.6
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
0
6.6
N.A.
13.3
80
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
26.6
13.3
13.3
N.A.
26.6
86.6
6.6
20
Percent
Protein Identity:
N.A.
55.1
N.A.
51.4
41.9
29.4
Protein Similarity:
N.A.
73.1
N.A.
69.7
59.8
42.6
P-Site Identity:
N.A.
80
N.A.
66.6
53.3
0
P-Site Similarity:
N.A.
93.3
N.A.
93.3
60
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
12
12
6
0
0
0
0
0
0
0
18
12
% A
% Cys:
0
0
6
0
0
0
0
0
0
0
0
18
0
0
0
% C
% Asp:
0
6
6
0
0
6
59
0
18
0
0
0
0
0
0
% D
% Glu:
12
36
42
6
0
0
0
0
6
0
0
0
0
65
0
% E
% Phe:
6
18
18
0
0
0
6
0
0
6
6
0
0
0
0
% F
% Gly:
0
0
0
6
0
0
6
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
12
0
0
0
0
6
0
0
59
0
24
% H
% Ile:
0
0
0
0
0
0
0
12
53
36
18
0
0
0
0
% I
% Lys:
0
0
0
0
12
6
0
6
0
0
0
0
0
6
0
% K
% Leu:
59
0
0
0
0
59
0
18
18
6
12
6
6
0
6
% L
% Met:
0
0
6
0
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
18
71
42
18
18
0
0
0
6
6
0
0
0
% N
% Pro:
6
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
12
0
0
12
0
0
0
0
0
0
0
6
0
0
% Q
% Arg:
0
6
0
0
0
0
6
0
0
6
59
0
18
12
0
% R
% Ser:
0
0
0
0
0
0
0
0
6
0
0
59
12
0
0
% S
% Thr:
6
18
0
6
6
6
0
0
0
12
0
0
0
0
0
% T
% Val:
0
0
6
0
0
0
6
12
0
18
0
12
0
0
53
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _