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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP5C
All Species:
30
Human Site:
Y434
Identified Species:
41.25
UniProt:
P53041
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53041
NP_006238.1
499
56879
Y434
H
E
V
K
A
E
G
Y
E
V
A
H
G
G
R
Chimpanzee
Pan troglodytes
XP_512768
499
56846
Y434
H
E
V
K
A
E
G
Y
E
V
A
H
G
G
R
Rhesus Macaque
Macaca mulatta
XP_001111749
499
56900
Y434
H
E
V
K
A
E
G
Y
E
V
A
H
G
G
R
Dog
Lupus familis
XP_855029
473
53972
Y408
H
E
V
K
A
E
G
Y
E
V
A
H
G
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q60676
499
56828
Y434
H
E
V
K
A
E
G
Y
E
V
A
H
G
G
R
Rat
Rattus norvegicus
P53042
499
56898
Y434
H
E
V
K
A
E
G
Y
E
V
A
H
G
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P48463
309
35545
M245
S
R
A
H
Q
L
V
M
E
G
Y
N
W
C
H
Frog
Xenopus laevis
Q6IP91
307
35104
E243
R
A
H
Q
L
V
M
E
G
Y
K
W
H
F
N
Zebra Danio
Brachydanio rerio
A9JRC7
307
35078
E243
R
A
H
Q
L
V
M
E
G
Y
K
W
H
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23696
309
35450
M245
S
R
A
H
Q
L
V
M
E
G
Y
N
W
C
H
Honey Bee
Apis mellifera
XP_624242
489
56031
Y425
H
E
V
K
N
D
G
Y
E
V
G
H
D
G
K
Nematode Worm
Caenorhab. elegans
Q9XW79
333
37341
E269
R
A
H
Q
L
V
M
E
G
Y
K
W
H
F
N
Sea Urchin
Strong. purpuratus
XP_796785
500
56974
H431
L
E
Y
I
V
R
S
H
E
V
K
N
D
G
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150042
483
54661
H419
H
E
V
K
D
E
G
H
E
I
E
H
D
G
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84XU2
538
60264
Y474
H
E
V
K
D
E
G
Y
E
V
E
H
D
G
K
Baker's Yeast
Sacchar. cerevisiae
P53043
513
57976
V441
H
E
L
R
M
G
G
V
Q
F
E
Q
K
G
K
Red Bread Mold
Neurospora crassa
Q9UW86
308
35549
I244
Q
K
H
D
M
D
L
I
C
R
A
H
Q
V
V
Conservation
Percent
Protein Identity:
100
99.8
99.4
91.5
N.A.
98
98
N.A.
N.A.
27.4
29
28.8
N.A.
26.8
63.7
30
64.6
Protein Similarity:
100
100
99.8
93.1
N.A.
99.1
99.4
N.A.
N.A.
40.4
40.2
40
N.A.
39.6
79.9
43
81.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
0
0
N.A.
6.6
66.6
0
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
6.6
6.6
N.A.
13.3
80
6.6
40
Percent
Protein Identity:
N.A.
55.1
N.A.
51.4
41.9
29.4
Protein Similarity:
N.A.
73.1
N.A.
69.7
59.8
42.6
P-Site Identity:
N.A.
60
N.A.
73.3
26.6
13.3
P-Site Similarity:
N.A.
80
N.A.
80
53.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
18
12
0
36
0
0
0
0
0
42
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
6
0
0
0
0
12
0
% C
% Asp:
0
0
0
6
12
12
0
0
0
0
0
0
24
0
0
% D
% Glu:
0
65
0
0
0
48
0
18
71
0
18
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
6
0
0
0
18
0
% F
% Gly:
0
0
0
0
0
6
59
0
18
12
6
0
36
65
0
% G
% His:
59
0
24
12
0
0
0
12
0
0
0
59
18
0
12
% H
% Ile:
0
0
0
6
0
0
0
6
0
6
0
0
0
0
0
% I
% Lys:
0
6
0
53
0
0
0
0
0
0
24
0
6
0
24
% K
% Leu:
6
0
6
0
18
12
6
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
12
0
18
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
6
0
0
0
0
0
0
18
0
0
18
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
6
0
0
18
12
0
0
0
6
0
0
6
6
0
0
% Q
% Arg:
18
12
0
6
0
6
0
0
0
6
0
0
0
0
36
% R
% Ser:
12
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
53
0
6
18
12
6
0
53
0
0
0
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
18
12
0
0
% W
% Tyr:
0
0
6
0
0
0
0
48
0
18
12
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _