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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK1
All Species:
13.03
Human Site:
T6
Identified Species:
17.92
UniProt:
P53350
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53350
NP_005021.2
603
68255
T6
_
_
M
S
A
A
V
T
A
G
K
L
A
R
A
Chimpanzee
Pan troglodytes
XP_001163623
603
68223
T6
_
_
M
S
A
A
V
T
A
G
K
L
A
R
A
Rhesus Macaque
Macaca mulatta
XP_001092070
603
68240
T6
_
_
M
S
A
A
V
T
A
G
K
L
A
R
A
Dog
Lupus familis
XP_547091
832
93293
T234
G
N
M
S
A
A
A
T
A
G
K
L
A
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q07832
603
68282
K6
_
_
M
N
A
A
A
K
A
G
K
L
A
R
A
Rat
Rattus norvegicus
Q62673
603
68295
K6
_
_
M
N
A
A
A
K
A
G
K
L
A
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505317
482
55166
Chicken
Gallus gallus
NP_001025810
595
66904
A12
G
G
K
A
R
P
V
A
A
V
E
P
A
R
A
Frog
Xenopus laevis
P70032
598
68193
E14
K
K
L
T
V
A
P
E
A
A
K
P
P
G
I
Zebra Danio
Brachydanio rerio
NP_001003890
595
67743
A6
_
_
M
S
A
A
I
A
K
P
S
A
K
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
E6
_
_
M
A
A
K
P
E
D
K
S
T
D
I
P
Honey Bee
Apis mellifera
XP_396707
575
66141
K6
_
_
M
S
K
D
E
K
E
C
V
I
P
D
V
Nematode Worm
Caenorhab. elegans
P34331
649
73615
N6
_
_
M
N
R
L
P
N
I
A
K
P
P
Q
K
Sea Urchin
Strong. purpuratus
XP_784826
587
66895
K6
_
_
M
A
S
R
H
K
E
D
L
R
V
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
K10
P
K
A
T
S
T
S
K
T
D
N
I
D
Q
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9STV4
445
50410
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
D11
G
P
L
K
A
I
N
D
K
Q
L
N
T
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.8
69.5
N.A.
95
94.1
N.A.
69.3
80
79.7
74.3
N.A.
50.7
51.4
49.9
59.3
Protein Similarity:
100
99.8
99.8
71
N.A.
97.6
96.8
N.A.
74.7
89.8
90.5
87.5
N.A.
69.4
69.9
66.2
76.4
P-Site Identity:
100
100
100
80
N.A.
76.9
76.9
N.A.
0
33.3
20
30.7
N.A.
15.3
15.3
15.3
7.6
P-Site Similarity:
100
100
100
86.6
N.A.
84.6
84.6
N.A.
0
60
33.3
46.1
N.A.
23
23
30.7
30.7
Percent
Protein Identity:
N.A.
31.7
N.A.
26
33.9
N.A.
Protein Similarity:
N.A.
50.1
N.A.
40.4
51.6
N.A.
P-Site Identity:
N.A.
0
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
18
53
48
18
12
48
12
0
6
42
0
42
% A
% Cys:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
6
0
6
6
12
0
0
12
6
0
% D
% Glu:
0
0
0
0
0
0
6
12
12
0
6
0
0
0
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
18
6
0
0
0
0
0
0
0
36
0
0
0
6
0
% G
% His:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
6
6
0
6
0
0
12
0
6
12
% I
% Lys:
6
12
6
6
6
6
0
30
12
6
48
0
6
6
6
% K
% Leu:
0
0
12
0
0
6
0
0
0
0
12
36
0
0
0
% L
% Met:
0
0
65
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
18
0
0
6
6
0
0
6
6
0
0
0
% N
% Pro:
6
6
0
0
0
6
18
0
0
6
0
18
18
6
6
% P
% Gln:
0
0
0
0
0
0
0
0
0
6
0
0
0
12
0
% Q
% Arg:
0
0
0
0
12
6
0
0
0
0
0
6
0
48
0
% R
% Ser:
0
0
0
36
12
0
6
0
0
0
12
0
0
0
12
% S
% Thr:
0
0
0
12
0
6
0
24
6
0
0
6
6
0
0
% T
% Val:
0
0
0
0
6
0
24
0
0
6
6
0
6
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
59
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% _