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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DAPK1
All Species:
19.39
Human Site:
S745
Identified Species:
42.67
UniProt:
P53355
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53355
NP_004929.2
1430
160073
S745
S
K
P
T
V
S
V
S
I
N
N
L
Y
P
G
Chimpanzee
Pan troglodytes
XP_001140200
1430
160025
S745
S
K
P
T
V
S
V
S
I
N
N
L
Y
P
G
Rhesus Macaque
Macaca mulatta
XP_001084634
1430
160024
S745
S
K
P
T
V
S
V
S
I
N
N
L
Y
P
G
Dog
Lupus familis
XP_541259
1430
159848
S745
S
K
P
A
V
S
V
S
I
S
N
L
Y
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q80YE7
1442
161423
S745
A
K
P
T
V
S
V
S
I
N
N
L
Y
P
G
Rat
Rattus norvegicus
O88764
448
51431
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026784
974
109076
G359
I
N
D
D
N
V
P
G
L
Q
H
L
L
G
S
Frog
Xenopus laevis
NP_001086727
1427
159871
I745
A
K
T
V
S
V
S
I
S
D
L
Y
P
G
C
Zebra Danio
Brachydanio rerio
NP_001093460
1439
159594
S745
P
A
V
S
V
S
I
S
N
L
Y
P
G
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490840
1425
158950
D740
S
V
T
R
R
I
S
D
H
Y
S
P
S
S
S
Sea Urchin
Strong. purpuratus
XP_780774
1084
119703
D468
G
T
I
P
G
A
G
D
F
T
F
L
E
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.3
95.5
N.A.
94.3
24.2
N.A.
N.A.
60.7
86
74.7
N.A.
N.A.
N.A.
34.5
29.5
Protein Similarity:
100
99.9
99.7
97.9
N.A.
97.5
28.8
N.A.
N.A.
65.8
93.8
87.2
N.A.
N.A.
N.A.
54.4
45.9
P-Site Identity:
100
100
100
86.6
N.A.
93.3
0
N.A.
N.A.
6.6
6.6
20
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
0
N.A.
N.A.
20
20
33.3
N.A.
N.A.
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
0
10
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% C
% Asp:
0
0
10
10
0
0
0
19
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
10
0
0
10
0
% F
% Gly:
10
0
0
0
10
0
10
10
0
0
0
0
10
19
46
% G
% His:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% H
% Ile:
10
0
10
0
0
10
10
10
46
0
0
0
0
0
0
% I
% Lys:
0
55
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
10
10
10
64
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
0
0
0
10
37
46
0
0
0
0
% N
% Pro:
10
0
46
10
0
0
10
0
0
0
0
19
10
46
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
46
0
0
10
10
55
19
55
10
10
10
0
10
10
28
% S
% Thr:
0
10
19
37
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
10
10
10
55
19
46
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
10
10
46
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _