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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARFIP1 All Species: 31.52
Human Site: S312 Identified Species: 57.78
UniProt: P53367 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53367 NP_001020764.1 373 41738 S312 D K M R N D V S V K L K F L E
Chimpanzee Pan troglodytes XP_001146574 470 52029 S409 D K M R N D V S V K L K F L E
Rhesus Macaque Macaca mulatta XP_001086103 477 53412 F421 D V S V K L K F L E E N K V K
Dog Lupus familis XP_532691 373 41702 S312 D K M R N D V S I K L K F L E
Cat Felis silvestris
Mouse Mus musculus NP_001074562 373 41500 S312 D K M R S D V S V K L K F L E
Rat Rattus norvegicus Q9JHU5 366 40761 S305 D K M R S D V S V K L K F L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514230 373 41683 S312 D K M R N D V S I K L K F L E
Chicken Gallus gallus XP_001233078 373 41527 S312 D K M R N D V S I K L K F L E
Frog Xenopus laevis NP_001080149 342 38707 L295 E E N K V K V L H N Q L V L F
Zebra Danio Brachydanio rerio NP_998533 339 38452 L292 E E N K V K V L H N Q L I L F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396054 330 37364 V283 L D E N R I K V M H K Q L L L
Nematode Worm Caenorhab. elegans P34445 307 33896 R260 M R L L E E N R I S V V A A Q
Sea Urchin Strong. purpuratus XP_787151 403 44835 S342 D K L R Q D V S V K L R F L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51 63.5 97.5 N.A. 92.4 91.1 N.A. 92.7 89.5 78.2 69.1 N.A. N.A. 44.7 27.3 45.6
Protein Similarity: 100 60.8 68.3 98.9 N.A. 95.9 94.3 N.A. 96.5 94.3 86.5 79.6 N.A. N.A. 65.4 49 62
P-Site Identity: 100 100 6.6 93.3 N.A. 93.3 93.3 N.A. 93.3 93.3 13.3 13.3 N.A. N.A. 6.6 0 73.3
P-Site Similarity: 100 100 33.3 100 N.A. 100 100 N.A. 100 100 33.3 33.3 N.A. N.A. 20 40 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 70 8 0 0 0 62 0 0 0 0 0 0 0 0 8 % D
% Glu: 16 16 8 0 8 8 0 0 0 8 8 0 0 0 54 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 62 0 16 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 16 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 31 0 0 0 8 0 0 % I
% Lys: 0 62 0 16 8 16 16 0 0 62 8 54 8 0 8 % K
% Leu: 8 0 16 8 0 8 0 16 8 0 62 16 8 85 8 % L
% Met: 8 0 54 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 16 8 39 0 8 0 0 16 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 16 8 0 0 8 % Q
% Arg: 0 8 0 62 8 0 0 8 0 0 0 8 0 0 0 % R
% Ser: 0 0 8 0 16 0 0 62 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 8 0 8 16 0 77 8 39 0 8 8 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _