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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARFIP1 All Species: 36.67
Human Site: T253 Identified Species: 67.22
UniProt: P53367 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53367 NP_001020764.1 373 41738 T253 V N K T I E D T L M T V K Q Y
Chimpanzee Pan troglodytes XP_001146574 470 52029 T350 V N K T I E D T L M T V K Q Y
Rhesus Macaque Macaca mulatta XP_001086103 477 53412 T362 V N K T I E D T L M T V K Q I
Dog Lupus familis XP_532691 373 41702 T253 V N K T I E D T L M T V K Q Y
Cat Felis silvestris
Mouse Mus musculus NP_001074562 373 41500 T253 V N K T I E D T L M T V K Q Y
Rat Rattus norvegicus Q9JHU5 366 40761 T246 V N K T I E D T L M T V K Q Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514230 373 41683 T253 V N K T I E D T L M T V K Q Y
Chicken Gallus gallus XP_001233078 373 41527 T253 V N K T I E D T L L T V K Q Y
Frog Xenopus laevis NP_001080149 342 38707 Y236 Y E A S R I E Y D A Y R T D L
Zebra Danio Brachydanio rerio NP_998533 339 38452 Y233 Y E A A R I E Y D A Y R T D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396054 330 37364 Y224 Y E T A R I E Y D A Y R T D L
Nematode Worm Caenorhab. elegans P34445 307 33896 A201 T I Y N T E S A R I E Y D V D
Sea Urchin Strong. purpuratus XP_787151 403 44835 T283 C N K T M E D T L L T V K A Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51 63.5 97.5 N.A. 92.4 91.1 N.A. 92.7 89.5 78.2 69.1 N.A. N.A. 44.7 27.3 45.6
Protein Similarity: 100 60.8 68.3 98.9 N.A. 95.9 94.3 N.A. 96.5 94.3 86.5 79.6 N.A. N.A. 65.4 49 62
P-Site Identity: 100 100 93.3 100 N.A. 100 100 N.A. 100 93.3 0 0 N.A. N.A. 0 6.6 73.3
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 100 100 13.3 6.6 N.A. N.A. 6.6 13.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 16 0 0 0 8 0 24 0 0 0 8 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 70 0 24 0 0 0 8 24 8 % D
% Glu: 0 24 0 0 0 77 24 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 62 24 0 0 0 8 0 0 0 0 8 % I
% Lys: 0 0 70 0 0 0 0 0 0 0 0 0 70 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 70 16 0 0 0 0 24 % L
% Met: 0 0 0 0 8 0 0 0 0 54 0 0 0 0 0 % M
% Asn: 0 70 0 8 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 62 0 % Q
% Arg: 0 0 0 0 24 0 0 0 8 0 0 24 0 0 0 % R
% Ser: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % S
% Thr: 8 0 8 70 8 0 0 70 0 0 70 0 24 0 0 % T
% Val: 62 0 0 0 0 0 0 0 0 0 0 70 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 24 0 8 0 0 0 0 24 0 0 24 8 0 0 62 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _