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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARFIP1
All Species:
30.91
Human Site:
Y172
Identified Species:
56.67
UniProt:
P53367
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53367
NP_001020764.1
373
41738
Y172
L
R
D
N
K
K
K
Y
E
N
I
L
K
L
A
Chimpanzee
Pan troglodytes
XP_001146574
470
52029
K269
I
K
N
P
A
M
E
K
L
E
L
V
R
K
W
Rhesus Macaque
Macaca mulatta
XP_001086103
477
53412
Y281
L
R
D
N
K
K
K
Y
E
N
I
L
K
L
A
Dog
Lupus familis
XP_532691
373
41702
Y172
L
R
D
N
K
K
K
Y
E
N
I
L
R
L
A
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074562
373
41500
Y172
L
R
D
N
K
K
K
Y
E
N
I
L
K
L
A
Rat
Rattus norvegicus
Q9JHU5
366
40761
Y165
L
R
D
N
K
K
K
Y
E
N
I
L
K
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514230
373
41683
Y172
L
R
D
N
K
K
K
Y
E
N
I
L
K
L
A
Chicken
Gallus gallus
XP_001233078
373
41527
Y172
L
R
D
N
K
K
K
Y
E
N
I
L
K
L
A
Frog
Xenopus laevis
NP_001080149
342
38707
L155
A
Q
T
L
S
T
Q
L
F
Q
M
V
Q
T
Q
Zebra Danio
Brachydanio rerio
NP_998533
339
38452
L152
A
Q
T
L
C
T
Q
L
E
Q
M
L
M
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396054
330
37364
F143
S
R
A
L
A
S
H
F
H
H
V
V
Q
T
Q
Nematode Worm
Caenorhab. elegans
P34445
307
33896
F120
V
V
A
A
A
K
N
F
S
H
V
L
T
Q
M
Sea Urchin
Strong. purpuratus
XP_787151
403
44835
Y202
L
R
D
T
Q
R
K
Y
A
H
I
L
K
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51
63.5
97.5
N.A.
92.4
91.1
N.A.
92.7
89.5
78.2
69.1
N.A.
N.A.
44.7
27.3
45.6
Protein Similarity:
100
60.8
68.3
98.9
N.A.
95.9
94.3
N.A.
96.5
94.3
86.5
79.6
N.A.
N.A.
65.4
49
62
P-Site Identity:
100
0
100
93.3
N.A.
100
100
N.A.
100
100
0
13.3
N.A.
N.A.
6.6
13.3
60
P-Site Similarity:
100
46.6
100
100
N.A.
100
100
N.A.
100
100
33.3
33.3
N.A.
N.A.
40
40
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
16
8
24
0
0
0
8
0
0
0
0
0
54
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
62
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
62
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
16
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
8
24
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
62
0
0
0
0
% I
% Lys:
0
8
0
0
54
62
62
8
0
0
0
0
54
8
0
% K
% Leu:
62
0
0
24
0
0
0
16
8
0
8
77
0
62
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
16
0
8
0
8
% M
% Asn:
0
0
8
54
0
0
8
0
0
54
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
16
0
0
8
0
16
0
0
16
0
0
16
8
24
% Q
% Arg:
0
70
0
0
0
8
0
0
0
0
0
0
16
0
0
% R
% Ser:
8
0
0
0
8
8
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
16
8
0
16
0
0
0
0
0
0
8
24
8
% T
% Val:
8
8
0
0
0
0
0
0
0
0
16
24
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _