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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARFIP1 All Species: 37.27
Human Site: Y216 Identified Species: 68.33
UniProt: P53367 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53367 NP_001020764.1 373 41738 Y216 E L H E E F G Y N A D T Q K L
Chimpanzee Pan troglodytes XP_001146574 470 52029 Y313 E L H E E F G Y N A D T Q K L
Rhesus Macaque Macaca mulatta XP_001086103 477 53412 Y325 E L H E E F G Y N A D T Q K L
Dog Lupus familis XP_532691 373 41702 Y216 E L H E E F G Y N A D T Q K L
Cat Felis silvestris
Mouse Mus musculus NP_001074562 373 41500 Y216 E L H E E F G Y N A D T Q K L
Rat Rattus norvegicus Q9JHU5 366 40761 Y209 E L H E E F G Y N A D T Q K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514230 373 41683 Y216 E L H E E F G Y N A D T Q K L
Chicken Gallus gallus XP_001233078 373 41527 Y216 E L H E E F G Y N A D T Q K L
Frog Xenopus laevis NP_001080149 342 38707 T199 L L A K N G E T L L G A M N F
Zebra Danio Brachydanio rerio NP_998533 339 38452 T196 L L A K N G E T L L G A I S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396054 330 37364 T187 N L T K N G E T L L G A L N F
Nematode Worm Caenorhab. elegans P34445 307 33896 E164 E T M R G V G E Q A A S L D A
Sea Urchin Strong. purpuratus XP_787151 403 44835 Y246 E L Q E E F S Y N A E T Q K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 51 63.5 97.5 N.A. 92.4 91.1 N.A. 92.7 89.5 78.2 69.1 N.A. N.A. 44.7 27.3 45.6
Protein Similarity: 100 60.8 68.3 98.9 N.A. 95.9 94.3 N.A. 96.5 94.3 86.5 79.6 N.A. N.A. 65.4 49 62
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 6.6 6.6 N.A. N.A. 6.6 20 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 13.3 13.3 N.A. N.A. 13.3 26.6 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 0 0 0 0 0 77 8 24 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 62 0 0 8 0 % D
% Glu: 77 0 0 70 70 0 24 8 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 70 0 0 0 0 0 0 0 0 24 % F
% Gly: 0 0 0 0 8 24 70 0 0 0 24 0 0 0 0 % G
% His: 0 0 62 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 0 24 0 0 0 0 0 0 0 0 0 70 0 % K
% Leu: 16 93 0 0 0 0 0 0 24 24 0 0 16 0 62 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 8 0 0 0 24 0 0 0 70 0 0 0 0 16 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 8 0 0 0 70 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 8 0 0 0 0 8 0 8 8 % S
% Thr: 0 8 8 0 0 0 0 24 0 0 0 70 0 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 70 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _