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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUDT6 All Species: 29.7
Human Site: S204 Identified Species: 59.39
UniProt: P53370 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53370 NP_009014.2 316 35679 S204 G I K S E F R S V L S I R Q Q
Chimpanzee Pan troglodytes XP_517426 316 35616 S204 G I K S E F R S I L S I R Q Q
Rhesus Macaque Macaca mulatta XP_001103787 316 35284 S204 G I K S E F R S L L S I R Q Q
Dog Lupus familis XP_540961 339 38590 S227 G I K S E F K S L L S I R Q Q
Cat Felis silvestris
Mouse Mus musculus Q8CH40 313 35179 S201 G V K S E F R S L L S I R Q Q
Rat Rattus norvegicus P70563 313 35273 S201 G V K S E F R S L L S I R Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P13420 217 24288 H113 L L S I R Q Q H N H P G A F G
Zebra Danio Brachydanio rerio NP_001082991 331 36703 S218 G V R S E F R S L L S L R Q Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195666 163 18745 G57 G I H T E F K G V L A F R Q Q
Poplar Tree Populus trichocarpa XP_002303483 286 32468 E180 D I D T E F V E I L A F S Q T
Maize Zea mays NP_001132721 316 35423 D207 G V D T E F V D V V A F R H A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SU14 282 31866 S174 E V L A F R Q S H K A I L K K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 95.2 76.1 N.A. 72.4 74.3 N.A. N.A. N.A. 50.3 53.4 N.A. N.A. N.A. N.A. 27.2
Protein Similarity: 100 100 96.5 84 N.A. 82.2 82.2 N.A. N.A. N.A. 57.5 68.8 N.A. N.A. N.A. N.A. 37.9
P-Site Identity: 100 93.3 93.3 86.6 N.A. 86.6 86.6 N.A. N.A. N.A. 0 73.3 N.A. N.A. N.A. N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 13.3 100 N.A. N.A. N.A. N.A. 80
Percent
Protein Identity: 29.7 31.3 N.A. 28.4 N.A. N.A.
Protein Similarity: 49 48.7 N.A. 46.5 N.A. N.A.
P-Site Identity: 33.3 33.3 N.A. 13.3 N.A. N.A.
P-Site Similarity: 53.3 60 N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 0 0 0 0 34 0 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 17 0 0 0 0 9 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 0 84 0 0 9 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 9 84 0 0 0 0 0 25 0 9 0 % F
% Gly: 75 0 0 0 0 0 0 9 0 0 0 9 0 0 9 % G
% His: 0 0 9 0 0 0 0 9 9 9 0 0 0 9 0 % H
% Ile: 0 50 0 9 0 0 0 0 17 0 0 59 0 0 0 % I
% Lys: 0 0 50 0 0 0 17 0 0 9 0 0 0 9 9 % K
% Leu: 9 9 9 0 0 0 0 0 42 75 0 9 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % P
% Gln: 0 0 0 0 0 9 17 0 0 0 0 0 0 75 67 % Q
% Arg: 0 0 9 0 9 9 50 0 0 0 0 0 75 0 0 % R
% Ser: 0 0 9 59 0 0 0 67 0 0 59 0 9 0 0 % S
% Thr: 0 0 0 25 0 0 0 0 0 0 0 0 0 0 9 % T
% Val: 0 42 0 0 0 0 17 0 25 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _