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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUDT6 All Species: 26.36
Human Site: S207 Identified Species: 52.73
UniProt: P53370 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53370 NP_009014.2 316 35679 S207 S E F R S V L S I R Q Q H T N
Chimpanzee Pan troglodytes XP_517426 316 35616 S207 S E F R S I L S I R Q Q H T N
Rhesus Macaque Macaca mulatta XP_001103787 316 35284 S207 S E F R S L L S I R Q Q H T N
Dog Lupus familis XP_540961 339 38590 S230 S E F K S L L S I R Q Q H A S
Cat Felis silvestris
Mouse Mus musculus Q8CH40 313 35179 S204 S E F R S L L S I R Q Q H R S
Rat Rattus norvegicus P70563 313 35273 S204 S E F R S L L S I R Q Q H R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P13420 217 24288 P116 I R Q Q H N H P G A F G K S D
Zebra Danio Brachydanio rerio NP_001082991 331 36703 S221 S E F R S L L S L R Q Q H T H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195666 163 18745 A60 T E F K G V L A F R Q Q H K V
Poplar Tree Populus trichocarpa XP_002303483 286 32468 A183 T E F V E I L A F S Q T H Q T
Maize Zea mays NP_001132721 316 35423 A210 T E F V D V V A F R H A H N V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SU14 282 31866 A177 A F R Q S H K A I L K K K T D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 95.2 76.1 N.A. 72.4 74.3 N.A. N.A. N.A. 50.3 53.4 N.A. N.A. N.A. N.A. 27.2
Protein Similarity: 100 100 96.5 84 N.A. 82.2 82.2 N.A. N.A. N.A. 57.5 68.8 N.A. N.A. N.A. N.A. 37.9
P-Site Identity: 100 93.3 93.3 73.3 N.A. 80 80 N.A. N.A. N.A. 0 80 N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. 20 100 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: 29.7 31.3 N.A. 28.4 N.A. N.A.
Protein Similarity: 49 48.7 N.A. 46.5 N.A. N.A.
P-Site Identity: 33.3 33.3 N.A. 20 N.A. N.A.
P-Site Similarity: 53.3 53.3 N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 34 0 9 0 9 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 17 % D
% Glu: 0 84 0 0 9 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 9 84 0 0 0 0 0 25 0 9 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 9 0 0 9 0 0 0 % G
% His: 0 0 0 0 9 9 9 0 0 0 9 0 84 0 9 % H
% Ile: 9 0 0 0 0 17 0 0 59 0 0 0 0 0 0 % I
% Lys: 0 0 0 17 0 0 9 0 0 0 9 9 17 9 0 % K
% Leu: 0 0 0 0 0 42 75 0 9 9 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 0 9 25 % N
% Pro: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % P
% Gln: 0 0 9 17 0 0 0 0 0 0 75 67 0 9 0 % Q
% Arg: 0 9 9 50 0 0 0 0 0 75 0 0 0 17 0 % R
% Ser: 59 0 0 0 67 0 0 59 0 9 0 0 0 9 25 % S
% Thr: 25 0 0 0 0 0 0 0 0 0 0 9 0 42 9 % T
% Val: 0 0 0 17 0 25 9 0 0 0 0 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _