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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUDT6 All Species: 24.85
Human Site: T126 Identified Species: 49.7
UniProt: P53370 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53370 NP_009014.2 316 35679 T126 E S D S S T L T L W L R E G P
Chimpanzee Pan troglodytes XP_517426 316 35616 T126 E S D S S T L T L W L R E G P
Rhesus Macaque Macaca mulatta XP_001103787 316 35284 T126 E S D S S T L T L W L G E G P
Dog Lupus familis XP_540961 339 38590 T149 E S D S S T L T L W L G E G P
Cat Felis silvestris
Mouse Mus musculus Q8CH40 313 35179 T123 K P H S S T L T L W L G E G P
Rat Rattus norvegicus P70563 313 35273 T123 E P H L S T L T L W L G E G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P13420 217 24288 H43 K L P G Y A T H Q V G V A G A
Zebra Danio Brachydanio rerio NP_001082991 331 36703 S140 R G D Q A V L S V W L A E G Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195666 163 18745
Poplar Tree Populus trichocarpa XP_002303483 286 32468 L110 I P E T P D T L P A N A S H T
Maize Zea mays NP_001132721 316 35423 T127 E E A Y L M M T Y W I P D E P
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SU14 282 31866 V104 P A N A S H V V G A G A L V I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 95.2 76.1 N.A. 72.4 74.3 N.A. N.A. N.A. 50.3 53.4 N.A. N.A. N.A. N.A. 27.2
Protein Similarity: 100 100 96.5 84 N.A. 82.2 82.2 N.A. N.A. N.A. 57.5 68.8 N.A. N.A. N.A. N.A. 37.9
P-Site Identity: 100 100 93.3 93.3 N.A. 73.3 73.3 N.A. N.A. N.A. 6.6 40 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 93.3 93.3 N.A. 80 73.3 N.A. N.A. N.A. 13.3 60 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: 29.7 31.3 N.A. 28.4 N.A. N.A.
Protein Similarity: 49 48.7 N.A. 46.5 N.A. N.A.
P-Site Identity: 0 26.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 46.6 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 9 9 9 0 0 0 17 0 25 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 42 0 0 9 0 0 0 0 0 0 9 0 0 % D
% Glu: 50 9 9 0 0 0 0 0 0 0 0 0 59 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 9 0 0 0 0 9 0 17 34 0 67 0 % G
% His: 0 0 17 0 0 9 0 9 0 0 0 0 0 9 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % I
% Lys: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 0 9 9 0 59 9 50 0 59 0 9 0 0 % L
% Met: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % N
% Pro: 9 25 9 0 9 0 0 0 9 0 0 9 0 0 59 % P
% Gln: 0 0 0 9 0 0 0 0 9 0 0 0 0 0 9 % Q
% Arg: 9 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % R
% Ser: 0 34 0 42 59 0 0 9 0 0 0 0 9 0 0 % S
% Thr: 0 0 0 9 0 50 17 59 0 0 0 0 0 0 9 % T
% Val: 0 0 0 0 0 9 9 9 9 9 0 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 67 0 0 0 0 0 % W
% Tyr: 0 0 0 9 9 0 0 0 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _