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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METAP1
All Species:
24.24
Human Site:
T96
Identified Species:
41.03
UniProt:
P53582
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53582
NP_055958.2
386
43215
T96
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Chimpanzee
Pan troglodytes
XP_001165908
367
40994
T96
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Rhesus Macaque
Macaca mulatta
XP_001099172
464
51572
T174
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Dog
Lupus familis
XP_544993
353
39779
S93
E
Q
A
L
K
G
T
S
Q
I
K
L
L
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BP48
386
43203
T96
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Rat
Rattus norvegicus
NP_001099946
386
43187
T96
P
H
Y
P
L
M
P
T
R
P
V
P
S
Y
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIM5
385
43103
T96
P
H
Y
P
L
T
P
T
R
P
V
P
S
Y
I
Frog
Xenopus laevis
Q7ZWV9
385
43178
M96
P
H
Y
P
L
T
P
M
R
P
V
P
S
Y
I
Zebra Danio
Brachydanio rerio
Q4QRK0
386
43548
M95
P
Y
Y
P
L
T
P
M
R
L
V
P
S
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651281
374
41708
P94
V
P
N
A
I
Q
R
P
D
Y
A
D
H
P
A
Honey Bee
Apis mellifera
XP_393865
377
42283
Y98
E
H
I
K
R
P
D
Y
A
T
H
P
T
G
L
Nematode Worm
Caenorhab. elegans
NP_500396
371
41724
P93
R
P
D
Y
A
L
H
P
Q
G
V
S
L
E
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SLN5
398
43974
K109
K
Q
Y
P
I
S
T
K
R
V
V
P
A
E
I
Baker's Yeast
Sacchar. cerevisiae
Q01662
387
43355
R97
A
S
Y
P
L
T
P
R
R
Y
V
P
E
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
82.7
90.1
N.A.
98.1
97.9
N.A.
N.A.
94.8
88
86.7
N.A.
61.6
66.3
60.3
N.A.
Protein Similarity:
100
95
83.1
91.1
N.A.
99.4
99.4
N.A.
N.A.
97.9
95
93.7
N.A.
75.1
79.5
72
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
93.3
86.6
66.6
N.A.
0
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
93.3
86.6
73.3
N.A.
6.6
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.7
47.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.1
62.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
0
0
0
8
0
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
8
0
8
0
0
8
0
8
0
% D
% Glu:
15
0
0
0
0
0
0
0
0
0
0
0
8
15
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
0
% G
% His:
0
58
0
0
0
0
8
0
0
0
8
0
8
0
0
% H
% Ile:
0
0
8
0
15
0
0
0
0
8
0
0
0
0
72
% I
% Lys:
8
0
0
8
8
0
0
8
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
8
65
8
0
0
0
8
0
8
15
0
8
% L
% Met:
0
0
0
0
0
36
0
15
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
58
15
0
72
0
8
65
15
0
50
0
79
0
8
0
% P
% Gln:
0
15
0
0
0
8
0
0
15
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
8
0
8
8
72
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
0
8
0
8
0
0
0
8
58
8
8
% S
% Thr:
0
0
0
0
0
29
15
43
0
8
0
0
8
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
8
79
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
72
8
0
0
0
8
0
15
0
0
0
50
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _