KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METAP1
All Species:
34.24
Human Site:
Y91
Identified Species:
57.95
UniProt:
P53582
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53582
NP_055958.2
386
43215
Y91
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
Chimpanzee
Pan troglodytes
XP_001165908
367
40994
Y91
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
Rhesus Macaque
Macaca mulatta
XP_001099172
464
51572
Y169
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
Dog
Lupus familis
XP_544993
353
39779
A88
G
M
S
E
S
E
Q
A
L
K
G
T
S
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BP48
386
43203
Y91
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
Rat
Rattus norvegicus
NP_001099946
386
43187
Y91
T
G
K
L
R
P
H
Y
P
L
M
P
T
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZIM5
385
43103
Y91
T
G
K
L
R
P
H
Y
P
L
T
P
T
R
P
Frog
Xenopus laevis
Q7ZWV9
385
43178
Y91
T
G
K
L
R
P
H
Y
P
L
T
P
M
R
P
Zebra Danio
Brachydanio rerio
Q4QRK0
386
43548
Y90
T
G
K
L
R
P
Y
Y
P
L
T
P
M
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651281
374
41708
N89
T
P
K
R
T
V
P
N
A
I
Q
R
P
D
Y
Honey Bee
Apis mellifera
XP_393865
377
42283
I93
R
R
E
V
P
E
H
I
K
R
P
D
Y
A
T
Nematode Worm
Caenorhab. elegans
NP_500396
371
41724
D88
P
D
H
I
P
R
P
D
Y
A
L
H
P
Q
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SLN5
398
43974
Y104
W
T
G
P
L
K
Q
Y
P
I
S
T
K
R
V
Baker's Yeast
Sacchar. cerevisiae
Q01662
387
43355
Y92
S
G
K
V
K
A
S
Y
P
L
T
P
R
R
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
82.7
90.1
N.A.
98.1
97.9
N.A.
N.A.
94.8
88
86.7
N.A.
61.6
66.3
60.3
N.A.
Protein Similarity:
100
95
83.1
91.1
N.A.
99.4
99.4
N.A.
N.A.
97.9
95
93.7
N.A.
75.1
79.5
72
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
93.3
86.6
73.3
N.A.
13.3
6.6
0
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
93.3
86.6
80
N.A.
20
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.7
47.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
69.1
62.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
8
8
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
8
0
0
0
8
0
8
0
% D
% Glu:
0
0
8
8
0
15
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
65
8
0
0
0
0
0
0
0
8
0
0
0
8
% G
% His:
0
0
8
0
0
0
58
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
0
15
0
0
0
0
8
% I
% Lys:
0
0
72
0
8
8
0
0
8
8
0
0
8
0
0
% K
% Leu:
0
0
0
58
8
0
0
0
8
65
8
0
0
0
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
36
0
15
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
8
15
58
15
0
72
0
8
65
15
0
50
% P
% Gln:
0
0
0
0
0
0
15
0
0
0
8
0
0
15
0
% Q
% Arg:
8
8
0
8
58
8
0
0
0
8
0
8
8
72
0
% R
% Ser:
8
0
8
0
8
0
8
0
0
0
8
0
8
0
0
% S
% Thr:
65
8
0
0
8
0
0
0
0
0
29
15
43
0
8
% T
% Val:
0
0
0
15
0
8
0
0
0
0
0
0
0
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
72
8
0
0
0
8
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _