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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MVD
All Species:
13.64
Human Site:
S146
Identified Species:
25
UniProt:
P53602
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53602
NP_002452.1
400
43405
S146
A
R
V
Y
G
V
E
S
D
L
S
E
V
A
R
Chimpanzee
Pan troglodytes
XP_523460
400
43351
S146
A
R
V
Y
G
V
E
S
D
L
S
E
V
A
R
Rhesus Macaque
Macaca mulatta
XP_001089404
401
43456
S146
A
R
V
Y
G
V
E
S
D
L
S
E
V
A
R
Dog
Lupus familis
XP_546783
400
43803
S146
A
Q
V
Y
G
V
D
S
D
L
S
E
V
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99JF5
401
44054
G147
A
Q
V
Y
G
V
E
G
D
L
S
E
V
A
R
Rat
Rattus norvegicus
Q62967
401
43884
G147
A
R
V
Y
G
V
E
G
D
L
S
E
V
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509372
412
45223
G158
A
R
L
Y
G
V
E
G
E
L
S
E
V
A
R
Chicken
Gallus gallus
XP_423130
366
39925
G126
R
L
A
R
K
R
R
G
D
D
A
A
A
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U403
400
44580
G145
S
Q
L
F
N
V
E
G
E
L
S
G
V
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573068
388
42814
L135
S
R
L
Y
D
I
P
L
N
E
E
L
T
T
V
Honey Bee
Apis mellifera
XP_001121619
338
37775
A114
A
G
L
A
S
S
A
A
G
Y
A
C
L
V
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_566995
419
46229
E148
A
K
L
M
N
V
D
E
D
P
S
H
L
S
A
Baker's Yeast
Sacchar. cerevisiae
P32377
396
44097
Q140
A
K
L
Y
Q
L
P
Q
S
T
S
E
I
S
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
95.7
86.7
N.A.
83.7
84.2
N.A.
71.8
60
N.A.
66.2
N.A.
48.7
46.2
N.A.
N.A.
Protein Similarity:
100
96.2
97
91.5
N.A.
88.7
89
N.A.
81.3
69.5
N.A.
80.7
N.A.
65
60.2
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
93.3
N.A.
80
6.6
N.A.
46.6
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
13.3
N.A.
80
N.A.
40
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.1
47.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.4
63.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
77
0
8
8
0
0
8
8
0
0
16
8
8
62
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
8
0
16
0
62
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
54
8
16
8
8
62
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
54
0
0
39
8
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
8
% I
% Lys:
0
16
0
0
8
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
47
0
0
8
0
8
0
62
0
8
16
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
16
0
0
8
0
0
0
8
0
% P
% Gln:
0
24
0
0
8
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
8
47
0
8
0
8
8
0
0
0
0
0
0
0
70
% R
% Ser:
16
0
0
0
8
8
0
31
8
0
77
0
0
16
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
8
8
0
% T
% Val:
0
0
47
0
0
70
0
0
0
0
0
0
62
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
70
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _