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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGGT1B All Species: 28.18
Human Site: S108 Identified Species: 51.67
UniProt: P53609 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53609 NP_005014.2 377 42368 S108 L G I P F N P S K A P G T A H
Chimpanzee Pan troglodytes XP_526978 377 42336 S108 L G I P F N P S K A P G T A H
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538560 377 42509 S108 L G I P F N P S K N P G T A H
Cat Felis silvestris
Mouse Mus musculus Q8BUY9 377 42336 S108 L G I P F N P S K N P G A A H
Rat Rattus norvegicus P53610 377 42396 S108 L G I P F N P S K N P G T A H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507519 389 43735 S120 L G I P F S P S K P P G T A H
Chicken Gallus gallus
Frog Xenopus laevis NP_001089525 372 41854 S103 L G L P F N P S K G H G L H H
Zebra Danio Brachydanio rerio NP_001025426 355 39953 S95 S H I G V P Y S S S K G P G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_525100 395 44092 A99 M V P K T E D A E I L E C M R
Honey Bee Apis mellifera XP_396384 335 37062 S76 I T G A G P R S G F Q P S T T
Nematode Worm Caenorhab. elegans P41992 335 37207 E76 L E R M S T E E I V N Y V L G
Sea Urchin Strong. purpuratus XP_786326 369 41025 T105 G S S T I G L T F N P S E K D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P20133 325 36647 S66 E V I S F V L S C W D D K Y G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 97.8 N.A. 96.8 97.6 N.A. 89.9 N.A. 79.3 70.5 N.A. 43 46.9 25.9 60.2
Protein Similarity: 100 100 N.A. 97.8 N.A. 98.6 99.4 N.A. 93.3 N.A. 89.3 83.2 N.A. 61.5 64.9 44.2 75.6
P-Site Identity: 100 100 N.A. 93.3 N.A. 86.6 93.3 N.A. 86.6 N.A. 66.6 20 N.A. 0 6.6 6.6 6.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 86.6 93.3 N.A. 93.3 N.A. 73.3 26.6 N.A. 20 20 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 8 0 16 0 0 8 47 8 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 8 8 0 0 8 % D
% Glu: 8 8 0 0 0 8 8 8 8 0 0 8 8 0 0 % E
% Phe: 0 0 0 0 62 0 0 0 8 8 0 0 0 0 0 % F
% Gly: 8 54 8 8 8 8 0 0 8 8 0 62 0 8 16 % G
% His: 0 8 0 0 0 0 0 0 0 0 8 0 0 8 54 % H
% Ile: 8 0 62 0 8 0 0 0 8 8 0 0 0 0 0 % I
% Lys: 0 0 0 8 0 0 0 0 54 0 8 0 8 8 0 % K
% Leu: 62 0 8 0 0 0 16 0 0 0 8 0 8 8 0 % L
% Met: 8 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 47 0 0 0 31 8 0 0 0 0 % N
% Pro: 0 0 8 54 0 16 54 0 0 8 54 8 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 8 % R
% Ser: 8 8 8 8 8 8 0 77 8 8 0 8 8 0 0 % S
% Thr: 0 8 0 8 8 8 0 8 0 0 0 0 39 8 8 % T
% Val: 0 16 0 0 8 8 0 0 0 8 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 8 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _