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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGGT1B All Species: 26.06
Human Site: Y199 Identified Species: 47.78
UniProt: P53609 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53609 NP_005014.2 377 42368 Y199 D M K K A I T Y I R R S M S Y
Chimpanzee Pan troglodytes XP_526978 377 42336 Y199 D M K K A I T Y I R R S M S Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538560 377 42509 Y199 D M K K A I N Y I R R S M S Y
Cat Felis silvestris
Mouse Mus musculus Q8BUY9 377 42336 Y199 D M K K A I S Y I R R S M S Y
Rat Rattus norvegicus P53610 377 42396 Y199 D M K K A I S Y I R R S M S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507519 389 43735 Y211 D M K K T I D Y I R R S M S Y
Chicken Gallus gallus
Frog Xenopus laevis NP_001089525 372 41854 Y194 D I E R S I D Y I R R S M S Y
Zebra Danio Brachydanio rerio NP_001025426 355 39953 D181 L D D W S G M D R Q K T I D Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_525100 395 44092 F190 N K E T M F Q F I T R S L R Y
Honey Bee Apis mellifera XP_396384 335 37062 W162 I S I I L N D W S G I D K T K
Nematode Worm Caenorhab. elegans P41992 335 37207 L162 S L A T C H L L G R L S T L N
Sea Urchin Strong. purpuratus XP_786326 369 41025 G192 Y M L Q D W S G I N K D K A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P20133 325 36647 L152 A L S I L G E L T S E V V D P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 97.8 N.A. 96.8 97.6 N.A. 89.9 N.A. 79.3 70.5 N.A. 43 46.9 25.9 60.2
Protein Similarity: 100 100 N.A. 97.8 N.A. 98.6 99.4 N.A. 93.3 N.A. 89.3 83.2 N.A. 61.5 64.9 44.2 75.6
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 86.6 N.A. 66.6 6.6 N.A. 26.6 0 13.3 13.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 86.6 N.A. 93.3 40 N.A. 53.3 13.3 20 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 39 0 0 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 54 8 8 0 8 0 24 8 0 0 0 16 0 16 0 % D
% Glu: 0 0 16 0 0 0 8 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 16 0 8 8 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 8 16 0 54 0 0 70 0 8 0 8 0 0 % I
% Lys: 0 8 47 47 0 0 0 0 0 0 16 0 16 0 8 % K
% Leu: 8 16 8 0 16 0 8 16 0 0 8 0 8 8 0 % L
% Met: 0 54 0 0 8 0 8 0 0 0 0 0 54 0 0 % M
% Asn: 8 0 0 0 0 8 8 0 0 8 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 8 0 0 8 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 8 62 62 0 0 8 0 % R
% Ser: 8 8 8 0 16 0 24 0 8 8 0 70 0 54 0 % S
% Thr: 0 0 0 16 8 0 16 0 8 8 0 8 8 8 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 8 % V
% Trp: 0 0 0 8 0 8 0 8 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 54 0 0 0 0 0 0 70 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _