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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPB1
All Species:
38.79
Human Site:
S491
Identified Species:
65.64
UniProt:
P53618
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53618
NP_001137533.1
953
107142
S491
G
E
I
P
I
V
E
S
E
I
K
K
E
A
G
Chimpanzee
Pan troglodytes
XP_001172023
953
107170
S491
G
E
I
P
I
V
E
S
E
I
K
K
E
A
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534069
1054
117865
S592
G
E
I
P
I
V
E
S
E
I
K
K
E
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIF7
953
107048
S491
G
E
I
P
I
V
E
S
E
I
K
K
E
A
G
Rat
Rattus norvegicus
P23514
953
106992
S491
G
E
I
P
I
V
E
S
E
I
K
K
E
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507656
953
106948
S491
G
E
V
P
I
V
E
S
E
I
K
K
E
A
G
Chicken
Gallus gallus
Q5ZIA5
953
107103
S491
G
E
I
P
I
V
E
S
E
I
K
K
E
A
G
Frog
Xenopus laevis
NP_001090083
953
106905
T491
G
E
V
P
I
V
E
T
E
L
K
K
E
S
G
Zebra Danio
Brachydanio rerio
NP_001002013
953
107075
N491
G
E
I
P
I
V
E
N
E
L
K
K
E
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P45437
964
107388
E488
E
V
P
M
V
E
A
E
Q
R
R
L
A
G
D
Honey Bee
Apis mellifera
XP_001120953
949
104712
A483
G
E
L
P
L
L
E
A
E
N
K
R
Q
A
G
Nematode Worm
Caenorhab. elegans
NP_494441
971
107512
S490
G
E
L
P
L
V
D
S
E
L
S
G
Q
E
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SV20
948
106059
V486
G
E
L
P
F
Y
S
V
S
E
E
S
E
P
T
Baker's Yeast
Sacchar. cerevisiae
P41810
973
109001
S492
G
E
V
P
I
L
Q
S
E
I
K
K
L
T
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
89.6
N.A.
99.2
99
N.A.
97.5
97.9
94.7
93.4
N.A.
67.1
69.7
60.1
N.A.
Protein Similarity:
100
99.7
N.A.
90.1
N.A.
99.7
99.7
N.A.
99.1
99.3
98.1
96.9
N.A.
81.1
82.6
75.8
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
93.3
100
73.3
86.6
N.A.
0
53.3
40
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
20
93.3
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.2
42.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.3
64.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
8
0
0
0
0
8
65
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% D
% Glu:
8
93
0
0
0
8
72
8
86
8
8
0
72
8
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
93
0
0
0
0
0
0
0
0
0
0
8
0
8
72
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
50
0
72
0
0
0
0
58
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
79
72
0
0
0
% K
% Leu:
0
0
22
0
15
15
0
0
0
22
0
8
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% N
% Pro:
0
0
8
93
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
8
0
8
0
0
0
15
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
8
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
65
8
0
8
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
8
% T
% Val:
0
8
22
0
8
72
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _