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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPB1
All Species:
36.06
Human Site:
S599
Identified Species:
61.03
UniProt:
P53618
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53618
NP_001137533.1
953
107142
S599
I
L
H
L
G
K
S
S
L
P
K
K
P
I
T
Chimpanzee
Pan troglodytes
XP_001172023
953
107170
S599
I
L
H
L
G
K
S
S
L
P
K
K
P
I
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534069
1054
117865
S700
I
L
H
L
G
K
S
S
L
P
K
K
P
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIF7
953
107048
S599
I
L
H
L
G
K
S
S
L
P
K
K
P
I
T
Rat
Rattus norvegicus
P23514
953
106992
S599
I
L
H
L
G
K
S
S
L
P
K
K
P
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507656
953
106948
S599
I
L
H
L
G
K
S
S
L
P
K
K
P
I
T
Chicken
Gallus gallus
Q5ZIA5
953
107103
S599
I
L
H
L
G
K
S
S
L
P
K
K
P
I
T
Frog
Xenopus laevis
NP_001090083
953
106905
S599
I
L
H
L
G
K
S
S
L
P
K
K
Q
I
T
Zebra Danio
Brachydanio rerio
NP_001002013
953
107075
S599
V
L
H
L
G
K
S
S
L
P
K
K
P
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P45437
964
107388
F612
L
H
L
G
K
S
G
F
P
S
K
P
I
T
N
Honey Bee
Apis mellifera
XP_001120953
949
104712
G590
V
M
Q
L
G
R
S
G
L
P
T
K
A
I
T
Nematode Worm
Caenorhab. elegans
NP_494441
971
107512
V608
L
C
I
V
H
Q
Q
V
N
E
D
D
L
D
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SV20
948
106059
G600
M
V
S
I
L
Q
L
G
Q
S
P
V
S
P
H
Baker's Yeast
Sacchar. cerevisiae
P41810
973
109001
D616
S
L
V
E
K
K
I
D
E
D
S
L
E
R
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
89.6
N.A.
99.2
99
N.A.
97.5
97.9
94.7
93.4
N.A.
67.1
69.7
60.1
N.A.
Protein Similarity:
100
99.7
N.A.
90.1
N.A.
99.7
99.7
N.A.
99.1
99.3
98.1
96.9
N.A.
81.1
82.6
75.8
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
93.3
93.3
N.A.
6.6
53.3
0
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
13.3
73.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.2
42.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70.3
64.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
8
8
8
0
8
0
% D
% Glu:
0
0
0
8
0
0
0
0
8
8
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
72
0
8
15
0
0
0
0
0
0
0
% G
% His:
0
8
65
0
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
58
0
8
8
0
0
8
0
0
0
0
0
8
72
0
% I
% Lys:
0
0
0
0
15
72
0
0
0
0
72
72
0
0
0
% K
% Leu:
15
72
8
72
8
0
8
0
72
0
0
8
8
0
0
% L
% Met:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
8
72
8
8
58
8
0
% P
% Gln:
0
0
8
0
0
15
8
0
8
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% R
% Ser:
8
0
8
0
0
8
72
65
0
15
8
0
8
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
72
% T
% Val:
15
8
8
8
0
0
0
8
0
0
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _