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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COPB1 All Species: 32.12
Human Site: T533 Identified Species: 54.36
UniProt: P53618 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53618 NP_001137533.1 953 107142 T533 A L S S S R P T K K E E D R P
Chimpanzee Pan troglodytes XP_001172023 953 107170 T533 A L S S S R P T K K E E D R P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534069 1054 117865 T634 A L S S S R P T K K E E E R P
Cat Felis silvestris
Mouse Mus musculus Q9JIF7 953 107048 T533 A L S S S R P T K K E E D R P
Rat Rattus norvegicus P23514 953 106992 T533 A L S S S R P T K K E E D R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507656 953 106948 A533 A L S S S R P A K K E E D R P
Chicken Gallus gallus Q5ZIA5 953 107103 T533 A L S S S R P T K K E E D R P
Frog Xenopus laevis NP_001090083 953 106905 A533 A L S S S R P A K K E E E R P
Zebra Danio Brachydanio rerio NP_001002013 953 107075 S533 A L S T S R P S K K E E D R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P45437 964 107388 A546 A Y S L A P V A K A E K R P P
Honey Bee Apis mellifera XP_001120953 949 104712 R524 A F S A T S A R K K E E K R P
Nematode Worm Caenorhab. elegans NP_494441 971 107512 T533 A L S S T V T T S K K N E K P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SV20 948 106059 S532 A A S E T T F S S P T V V Q G
Baker's Yeast Sacchar. cerevisiae P41810 973 109001 Q538 A F D V K T S Q K S V T D E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 89.6 N.A. 99.2 99 N.A. 97.5 97.9 94.7 93.4 N.A. 67.1 69.7 60.1 N.A.
Protein Similarity: 100 99.7 N.A. 90.1 N.A. 99.7 99.7 N.A. 99.1 99.3 98.1 96.9 N.A. 81.1 82.6 75.8 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 93.3 100 86.6 86.6 N.A. 33.3 53.3 46.6 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 100 93.3 100 N.A. 46.6 66.6 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 49.2 42.5 N.A.
Protein Similarity: N.A. N.A. N.A. 70.3 64.3 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 100 8 0 8 8 0 8 22 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 0 0 0 0 58 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 79 72 22 8 8 % E
% Phe: 0 15 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 0 0 86 79 8 8 8 8 0 % K
% Leu: 0 72 0 8 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 8 65 0 0 8 0 0 0 8 86 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 0 65 0 8 0 0 0 0 8 72 0 % R
% Ser: 0 0 93 65 65 8 8 15 15 8 0 0 0 0 0 % S
% Thr: 0 0 0 8 22 15 8 50 0 0 8 8 0 0 0 % T
% Val: 0 0 0 8 0 8 8 0 0 0 8 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _