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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPA
All Species:
44.85
Human Site:
S222
Identified Species:
75.9
UniProt:
P53621
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53621
NP_001091868.1
1224
138346
S222
P
T
M
P
L
I
V
S
G
A
D
D
R
Q
V
Chimpanzee
Pan troglodytes
XP_001171498
1224
138329
S222
P
T
M
P
L
I
V
S
G
A
D
D
R
Q
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536131
1241
139883
S239
P
T
M
P
L
I
V
S
G
A
D
D
R
Q
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIE6
1224
138428
S222
P
T
M
P
L
I
V
S
G
A
D
D
R
Q
V
Rat
Rattus norvegicus
O35142
905
102533
V39
A
S
L
Y
N
G
S
V
C
V
W
N
H
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026576
1224
138533
S222
P
T
M
P
L
I
V
S
G
A
D
D
R
Q
V
Frog
Xenopus laevis
NP_001086488
1224
138559
S222
P
T
M
P
L
I
V
S
G
A
D
D
R
Q
V
Zebra Danio
Brachydanio rerio
NP_001001941
1226
138438
S223
P
S
M
P
L
I
V
S
G
A
D
D
R
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O62621
914
102694
M49
M
N
Y
E
N
Q
Q
M
V
K
D
F
E
V
C
Honey Bee
Apis mellifera
XP_623198
1214
137977
S224
P
T
L
P
L
I
V
S
G
A
D
D
R
Q
I
Nematode Worm
Caenorhab. elegans
Q20168
1000
111088
M134
D
W
D
N
K
W
A
M
K
Q
S
F
E
G
H
Sea Urchin
Strong. purpuratus
XP_001179078
1211
136717
S210
P
T
M
P
L
I
L
S
A
A
D
D
R
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A40
1216
136548
S221
P
T
L
P
L
I
V
S
G
A
D
D
R
Q
V
Baker's Yeast
Sacchar. cerevisiae
P53622
1201
135589
S226
P
T
L
P
L
I
V
S
G
S
D
D
R
Q
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
96.8
N.A.
98.5
23.1
N.A.
N.A.
96.5
93.1
86.3
N.A.
20.1
73.3
20.7
77.5
Protein Similarity:
100
99.9
N.A.
97.7
N.A.
99.1
37.8
N.A.
N.A.
98.5
97.1
94.7
N.A.
37.9
85
39
87
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
N.A.
100
100
93.3
N.A.
6.6
86.6
0
80
P-Site Similarity:
100
100
N.A.
100
N.A.
100
26.6
N.A.
N.A.
100
100
100
N.A.
6.6
100
0
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.5
43.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
72.4
64.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
93.3
86.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
100
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
8
72
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% C
% Asp:
8
0
8
0
0
0
0
0
0
0
86
79
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
15
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
72
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
0
0
79
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
0
8
0
0
0
8
8
0
0
0
0
0
% K
% Leu:
0
0
29
0
79
0
8
0
0
0
0
0
0
0
0
% L
% Met:
8
0
58
0
0
0
0
15
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
8
15
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
79
0
0
79
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
8
0
0
8
0
0
0
72
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
79
0
0
% R
% Ser:
0
15
0
0
0
0
8
79
0
8
8
0
0
0
0
% S
% Thr:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
72
8
8
8
0
0
0
8
72
% V
% Trp:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _