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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPA
All Species:
45.15
Human Site:
T544
Identified Species:
76.41
UniProt:
P53621
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53621
NP_001091868.1
1224
138346
T544
E
S
G
V
F
I
Y
T
T
S
N
H
I
K
Y
Chimpanzee
Pan troglodytes
XP_001171498
1224
138329
T544
E
S
G
V
F
I
Y
T
T
S
N
H
I
K
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536131
1241
139883
T561
E
S
G
V
F
I
Y
T
T
S
N
H
I
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIE6
1224
138428
T544
E
S
G
V
F
I
Y
T
T
S
N
H
I
K
Y
Rat
Rattus norvegicus
O35142
905
102533
K318
N
G
K
I
I
W
A
K
H
S
E
V
Q
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026576
1224
138533
T544
E
S
G
V
F
I
Y
T
T
S
N
H
I
K
Y
Frog
Xenopus laevis
NP_001086488
1224
138559
T544
E
S
G
V
F
I
Y
T
T
S
N
H
I
K
Y
Zebra Danio
Brachydanio rerio
NP_001001941
1226
138438
T546
E
N
E
V
F
I
Y
T
T
S
N
H
I
K
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O62621
914
102694
L328
S
E
M
Q
Q
V
N
L
K
T
I
A
D
G
T
Honey Bee
Apis mellifera
XP_623198
1214
137977
T545
D
S
G
V
F
I
Y
T
T
S
N
H
I
K
Y
Nematode Worm
Caenorhab. elegans
Q20168
1000
111088
T413
F
A
V
R
E
S
A
T
N
V
K
I
K
K
N
Sea Urchin
Strong. purpuratus
XP_001179078
1211
136717
T532
E
S
G
V
F
I
Y
T
T
S
N
H
I
K
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A40
1216
136548
T546
D
N
G
V
F
I
Y
T
T
L
N
H
I
K
Y
Baker's Yeast
Sacchar. cerevisiae
P53622
1201
135589
S548
E
T
G
V
L
I
Y
S
T
L
N
H
I
R
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
96.8
N.A.
98.5
23.1
N.A.
N.A.
96.5
93.1
86.3
N.A.
20.1
73.3
20.7
77.5
Protein Similarity:
100
99.9
N.A.
97.7
N.A.
99.1
37.8
N.A.
N.A.
98.5
97.1
94.7
N.A.
37.9
85
39
87
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
N.A.
100
100
86.6
N.A.
0
93.3
13.3
100
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
N.A.
100
100
93.3
N.A.
13.3
100
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.5
43.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
72.4
64.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
80
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
15
0
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
65
8
8
0
8
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
8
0
0
0
72
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
72
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
79
0
0
0
% H
% Ile:
0
0
0
8
8
79
0
0
0
0
8
8
79
0
0
% I
% Lys:
0
0
8
0
0
0
0
8
8
0
8
0
8
79
0
% K
% Leu:
0
0
0
0
8
0
0
8
0
15
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
15
0
0
0
0
8
0
8
0
79
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
8
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
8
58
0
0
0
8
0
8
0
72
0
0
0
0
0
% S
% Thr:
0
8
0
0
0
0
0
79
79
8
0
0
0
0
8
% T
% Val:
0
0
8
79
0
8
0
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
79
0
0
0
0
0
0
0
79
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _