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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPA
All Species:
17.88
Human Site:
T839
Identified Species:
30.26
UniProt:
P53621
Number Species:
13
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53621
NP_001091868.1
1224
138346
T839
A
A
D
I
D
I
D
T
V
G
T
E
G
W
G
Chimpanzee
Pan troglodytes
XP_001171498
1224
138329
T839
A
A
D
I
D
I
D
T
V
G
T
E
G
W
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536131
1241
139883
T856
A
A
D
I
D
I
D
T
V
G
T
E
G
W
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIE6
1224
138428
T839
A
A
D
I
D
I
D
T
V
G
T
E
G
W
G
Rat
Rattus norvegicus
O35142
905
102533
N571
L
G
Y
I
P
K
D
N
R
L
Y
L
G
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026576
1224
138533
N839
A
A
D
I
D
I
D
N
V
G
T
E
G
W
G
Frog
Xenopus laevis
NP_001086488
1224
138559
T839
A
A
D
I
D
V
D
T
V
G
G
E
G
W
G
Zebra Danio
Brachydanio rerio
NP_001001941
1226
138438
A841
V
A
D
L
D
M
D
A
P
G
G
E
G
W
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O62621
914
102694
E581
R
I
Y
L
G
D
K
E
L
N
V
I
S
F
C
Honey Bee
Apis mellifera
XP_623198
1214
137977
D838
A
A
L
A
P
E
D
D
N
A
E
P
A
E
G
Nematode Worm
Caenorhab. elegans
Q20168
1000
111088
E667
A
L
Q
S
D
S
E
E
K
W
K
A
L
S
N
Sea Urchin
Strong. purpuratus
XP_001179078
1211
136717
A826
S
T
M
T
A
A
V
A
M
D
E
G
D
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A40
1216
136548
D839
D
E
E
D
V
E
G
D
W
G
E
E
L
D
I
Baker's Yeast
Sacchar. cerevisiae
P53622
1201
135589
E839
D
D
L
T
I
D
D
E
T
P
A
V
N
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
96.8
N.A.
98.5
23.1
N.A.
N.A.
96.5
93.1
86.3
N.A.
20.1
73.3
20.7
77.5
Protein Similarity:
100
99.9
N.A.
97.7
N.A.
99.1
37.8
N.A.
N.A.
98.5
97.1
94.7
N.A.
37.9
85
39
87
P-Site Identity:
100
100
N.A.
100
N.A.
100
20
N.A.
N.A.
93.3
86.6
60
N.A.
0
26.6
13.3
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
N.A.
93.3
93.3
73.3
N.A.
20
26.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.5
43.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
72.4
64.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
58
0
8
8
8
0
15
0
8
8
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
15
8
50
8
58
15
72
15
0
8
0
0
8
15
0
% D
% Glu:
0
8
8
0
0
15
8
22
0
0
22
58
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
0
0
8
0
8
0
0
58
15
8
58
0
65
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
50
8
36
0
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
8
8
0
8
0
8
0
0
0
8
% K
% Leu:
8
8
15
15
0
0
0
0
8
8
0
8
15
0
0
% L
% Met:
0
0
8
0
0
8
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
8
8
0
0
8
0
8
% N
% Pro:
0
0
0
0
15
0
0
0
8
8
0
8
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
8
0
0
8
0
8
0
0
0
0
0
0
8
8
0
% S
% Thr:
0
8
0
15
0
0
0
36
8
0
36
0
0
8
8
% T
% Val:
8
0
0
0
8
8
8
0
43
0
8
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
8
0
0
0
50
0
% W
% Tyr:
0
0
15
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _