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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPA
All Species:
40.91
Human Site:
Y249
Identified Species:
69.23
UniProt:
P53621
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53621
NP_001091868.1
1224
138346
Y249
V
D
T
C
R
G
H
Y
N
N
V
S
C
A
V
Chimpanzee
Pan troglodytes
XP_001171498
1224
138329
Y249
V
D
T
C
R
G
H
Y
N
N
V
S
C
A
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536131
1241
139883
Y266
V
D
T
C
R
G
H
Y
N
N
V
S
C
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIE6
1224
138428
Y249
V
D
T
C
R
G
H
Y
N
N
V
S
C
A
V
Rat
Rattus norvegicus
O35142
905
102533
V66
P
V
R
A
A
K
F
V
A
R
K
N
W
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026576
1224
138533
Y249
V
D
T
C
R
G
H
Y
N
N
V
S
C
A
V
Frog
Xenopus laevis
NP_001086488
1224
138559
Y249
V
D
T
C
R
G
H
Y
N
N
V
S
C
A
V
Zebra Danio
Brachydanio rerio
NP_001001941
1226
138438
Y250
L
D
T
C
R
G
H
Y
N
N
V
S
C
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O62621
914
102694
S76
K
N
W
I
L
T
G
S
D
D
M
Q
I
R
V
Honey Bee
Apis mellifera
XP_623198
1214
137977
Y251
V
D
T
C
R
G
H
Y
N
N
V
S
C
V
L
Nematode Worm
Caenorhab. elegans
Q20168
1000
111088
A161
D
N
N
T
F
A
T
A
S
L
D
K
T
V
K
Sea Urchin
Strong. purpuratus
XP_001179078
1211
136717
Y237
V
D
T
C
R
G
H
Y
N
N
V
S
C
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A40
1216
136548
M248
V
D
T
L
R
G
H
M
N
N
V
S
S
V
M
Baker's Yeast
Sacchar. cerevisiae
P53622
1201
135589
T253
V
D
T
C
R
G
H
T
N
N
V
D
S
V
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
96.8
N.A.
98.5
23.1
N.A.
N.A.
96.5
93.1
86.3
N.A.
20.1
73.3
20.7
77.5
Protein Similarity:
100
99.9
N.A.
97.7
N.A.
99.1
37.8
N.A.
N.A.
98.5
97.1
94.7
N.A.
37.9
85
39
87
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
N.A.
100
100
93.3
N.A.
6.6
86.6
0
93.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
N.A.
100
100
100
N.A.
33.3
93.3
13.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.5
43.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
72.4
64.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
8
0
8
8
0
0
0
0
58
0
% A
% Cys:
0
0
0
72
0
0
0
0
0
0
0
0
65
0
0
% C
% Asp:
8
79
0
0
0
0
0
0
8
8
8
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
79
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
79
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
15
% I
% Lys:
8
0
0
0
0
8
0
0
0
0
8
8
0
0
8
% K
% Leu:
8
0
0
8
8
0
0
0
0
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
8
% M
% Asn:
0
15
8
0
0
0
0
0
79
79
0
8
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
8
0
79
0
0
0
0
8
0
0
0
8
0
% R
% Ser:
0
0
0
0
0
0
0
8
8
0
0
72
15
0
0
% S
% Thr:
0
0
79
8
0
8
8
8
0
0
0
0
8
0
0
% T
% Val:
72
8
0
0
0
0
0
8
0
0
79
0
0
36
65
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _