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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSC
All Species:
12.73
Human Site:
S209
Identified Species:
21.54
UniProt:
P53634
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53634
NP_001805.3
463
51842
S209
I
R
R
S
G
G
H
S
R
K
I
P
R
P
K
Chimpanzee
Pan troglodytes
XP_508684
463
51907
S209
I
R
R
S
G
G
H
S
R
K
I
P
R
P
K
Rhesus Macaque
Macaca mulatta
XP_001104734
463
51874
S209
I
K
R
S
G
G
H
S
R
K
I
P
R
P
K
Dog
Lupus familis
XP_535784
481
54085
K230
M
R
R
A
G
G
R
K
I
P
R
P
K
P
T
Cat
Felis silvestris
Mouse
Mus musculus
P97821
462
52358
Q209
I
R
R
S
G
H
S
Q
R
I
P
R
P
K
P
Rat
Rattus norvegicus
P80067
462
52217
G209
I
R
R
S
G
H
S
G
R
I
L
R
P
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512140
469
52438
S215
F
K
R
S
G
G
R
S
F
P
N
P
R
P
K
Chicken
Gallus gallus
P43233
340
37569
S97
W
P
N
C
P
T
I
S
E
I
R
D
Q
G
S
Frog
Xenopus laevis
NP_001080511
458
51565
V210
G
R
N
S
R
I
P
V
R
P
R
P
A
P
M
Zebra Danio
Brachydanio rerio
NP_999887
455
50596
R210
S
R
I
P
R
R
V
R
P
V
T
V
A
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P43510
379
42386
F136
S
C
G
S
C
W
A
F
G
A
V
E
A
M
S
Sea Urchin
Strong. purpuratus
XP_001201161
459
51309
V212
P
R
P
A
P
A
I
V
T
N
Q
A
K
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q10717
360
39181
A117
M
S
W
E
E
F
R
A
T
R
L
G
A
A
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H166
358
38941
F115
A
D
L
T
W
Q
E
F
Q
R
T
K
L
G
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.6
79
N.A.
77.7
78.6
N.A.
72
22.8
62.4
63.2
N.A.
N.A.
N.A.
23.3
54.8
Protein Similarity:
100
99.7
97.4
85.4
N.A.
86.6
87
N.A.
83.5
38
77.3
77.1
N.A.
N.A.
N.A.
38.2
71.4
P-Site Identity:
100
100
93.3
40
N.A.
40
40
N.A.
60
6.6
33.3
6.6
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
60
N.A.
40
46.6
N.A.
66.6
13.3
33.3
6.6
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
N.A.
27.8
N.A.
27
N.A.
N.A.
Protein Similarity:
N.A.
42.5
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
15
0
8
8
8
0
8
0
8
29
15
15
% A
% Cys:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
8
% D
% Glu:
0
0
0
8
8
0
8
0
8
0
0
8
0
0
0
% E
% Phe:
8
0
0
0
0
8
0
15
8
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
50
36
0
8
8
0
0
8
0
15
0
% G
% His:
0
0
0
0
0
15
22
0
0
0
0
0
0
0
0
% H
% Ile:
36
0
8
0
0
8
15
0
8
22
22
0
0
0
0
% I
% Lys:
0
15
0
0
0
0
0
8
0
22
0
8
15
15
29
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
15
0
8
0
0
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
15
0
0
0
0
0
0
8
8
0
0
0
0
% N
% Pro:
8
8
8
8
15
0
8
0
8
22
8
43
15
43
15
% P
% Gln:
0
0
0
0
0
8
0
8
8
0
8
0
8
0
8
% Q
% Arg:
0
58
50
0
15
8
22
8
43
15
22
15
29
8
0
% R
% Ser:
15
8
0
58
0
0
15
36
0
0
0
0
0
0
15
% S
% Thr:
0
0
0
8
0
8
0
0
15
0
15
0
0
0
8
% T
% Val:
0
0
0
0
0
0
8
15
0
8
8
8
0
0
0
% V
% Trp:
8
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _