KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSC
All Species:
16.06
Human Site:
S257
Identified Species:
27.18
UniProt:
P53634
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53634
NP_001805.3
463
51842
S257
R
N
Q
A
S
C
G
S
C
Y
S
F
A
S
M
Chimpanzee
Pan troglodytes
XP_508684
463
51907
S257
R
N
Q
A
S
C
G
S
C
Y
S
F
A
S
M
Rhesus Macaque
Macaca mulatta
XP_001104734
463
51874
S257
R
N
Q
A
S
C
G
S
C
Y
S
F
A
S
V
Dog
Lupus familis
XP_535784
481
54085
Y278
Q
A
S
C
G
S
C
Y
A
F
A
S
T
V
M
Cat
Felis silvestris
Mouse
Mus musculus
P97821
462
52358
C257
N
Q
E
S
C
G
S
C
Y
S
F
A
S
M
G
Rat
Rattus norvegicus
P80067
462
52217
C257
N
Q
E
S
C
G
S
C
Y
S
F
A
S
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512140
469
52438
S263
R
N
Q
A
S
C
G
S
C
Y
S
F
A
S
M
Chicken
Gallus gallus
P43233
340
37569
E145
L
L
S
C
C
G
F
E
C
G
M
G
C
N
G
Frog
Xenopus laevis
NP_001080511
458
51565
S258
G
S
C
Y
A
F
A
S
M
G
M
L
E
S
R
Zebra Danio
Brachydanio rerio
NP_999887
455
50596
G258
C
Y
S
F
A
T
M
G
M
L
E
A
R
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P43510
379
42386
R184
G
D
P
L
A
A
W
R
Y
W
V
K
D
G
I
Sea Urchin
Strong. purpuratus
XP_001201161
459
51309
L260
A
F
G
S
L
A
M
L
E
S
R
L
R
I
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q10717
360
39181
G165
V
K
N
Q
G
H
C
G
S
C
W
T
F
S
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H166
358
38941
G163
V
K
D
Q
G
G
C
G
S
C
W
T
F
S
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.6
79
N.A.
77.7
78.6
N.A.
72
22.8
62.4
63.2
N.A.
N.A.
N.A.
23.3
54.8
Protein Similarity:
100
99.7
97.4
85.4
N.A.
86.6
87
N.A.
83.5
38
77.3
77.1
N.A.
N.A.
N.A.
38.2
71.4
P-Site Identity:
100
100
93.3
6.6
N.A.
0
0
N.A.
100
6.6
13.3
0
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
100
26.6
N.A.
20
20
N.A.
100
13.3
26.6
6.6
N.A.
N.A.
N.A.
26.6
6.6
Percent
Protein Identity:
N.A.
27.8
N.A.
27
N.A.
N.A.
Protein Similarity:
N.A.
42.5
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
29
22
15
8
0
8
0
8
22
29
0
8
% A
% Cys:
8
0
8
15
22
29
22
15
36
15
0
0
8
0
0
% C
% Asp:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
15
0
0
0
0
8
8
0
8
0
8
0
0
% E
% Phe:
0
8
0
8
0
8
8
0
0
8
15
29
15
0
0
% F
% Gly:
15
0
8
0
22
29
29
22
0
15
0
8
0
8
22
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
0
15
0
0
0
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
8
8
0
8
8
0
0
8
0
8
0
15
0
8
0
% L
% Met:
0
0
0
0
0
0
15
0
15
0
15
0
0
8
29
% M
% Asn:
15
29
8
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
15
29
15
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
29
0
0
0
0
0
0
8
0
0
8
0
15
0
15
% R
% Ser:
0
8
22
22
29
8
15
36
15
22
29
8
15
50
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
15
8
0
15
% T
% Val:
15
0
0
0
0
0
0
0
0
0
8
0
0
15
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
8
15
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
0
8
22
29
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _