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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSC
All Species:
13.64
Human Site:
T325
Identified Species:
23.08
UniProt:
P53634
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53634
NP_001805.3
463
51842
T325
E
E
A
C
F
P
Y
T
G
T
D
S
P
C
K
Chimpanzee
Pan troglodytes
XP_508684
463
51907
T325
E
E
A
C
F
P
Y
T
G
T
D
S
P
C
K
Rhesus Macaque
Macaca mulatta
XP_001104734
463
51874
T325
E
E
A
C
F
P
Y
T
G
N
D
S
P
C
K
Dog
Lupus familis
XP_535784
481
54085
S346
A
C
F
S
Y
A
G
S
D
S
P
C
K
P
N
Cat
Felis silvestris
Mouse
Mus musculus
P97821
462
52358
A325
E
S
C
F
P
Y
T
A
K
D
S
P
C
K
P
Rat
Rattus norvegicus
P80067
462
52217
A325
E
N
C
F
P
Y
T
A
T
D
A
P
C
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512140
469
52438
T331
E
E
D
C
F
P
Y
T
A
R
D
T
Q
C
V
Chicken
Gallus gallus
P43233
340
37569
E213
P
R
C
S
R
H
C
E
P
G
Y
S
P
S
Y
Frog
Xenopus laevis
NP_001080511
458
51565
C326
Y
I
G
S
D
S
P
C
T
L
K
D
S
Y
Q
Zebra Danio
Brachydanio rerio
NP_999887
455
50596
P326
S
D
S
P
C
N
L
P
A
K
C
T
K
Y
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P43510
379
42386
F252
T
Y
S
E
D
K
F
F
G
A
S
A
Y
G
V
Sea Urchin
Strong. purpuratus
XP_001201161
459
51309
K328
D
I
S
C
S
K
E
K
A
G
C
R
R
Y
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q10717
360
39181
Y233
D
T
E
E
S
Y
P
Y
Q
G
V
N
G
I
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H166
358
38941
Y231
D
T
E
K
A
Y
P
Y
T
G
K
D
E
T
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.6
79
N.A.
77.7
78.6
N.A.
72
22.8
62.4
63.2
N.A.
N.A.
N.A.
23.3
54.8
Protein Similarity:
100
99.7
97.4
85.4
N.A.
86.6
87
N.A.
83.5
38
77.3
77.1
N.A.
N.A.
N.A.
38.2
71.4
P-Site Identity:
100
100
93.3
0
N.A.
6.6
6.6
N.A.
60
13.3
0
0
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
93.3
20
N.A.
6.6
6.6
N.A.
66.6
13.3
6.6
20
N.A.
N.A.
N.A.
26.6
20
Percent
Protein Identity:
N.A.
27.8
N.A.
27
N.A.
N.A.
Protein Similarity:
N.A.
42.5
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
22
0
8
8
0
15
22
8
8
8
0
0
0
% A
% Cys:
0
8
22
36
8
0
8
8
0
0
15
8
15
29
15
% C
% Asp:
22
8
8
0
15
0
0
0
8
15
29
15
0
0
0
% D
% Glu:
43
29
15
15
0
0
8
8
0
0
0
0
8
0
0
% E
% Phe:
0
0
8
15
29
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
8
0
29
29
0
0
8
8
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
8
0
15
0
8
8
8
15
0
15
15
22
% K
% Leu:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
8
0
8
0
0
8
% N
% Pro:
8
0
0
8
15
29
22
8
8
0
8
15
29
8
15
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
8
% Q
% Arg:
0
8
0
0
8
0
0
0
0
8
0
8
8
0
0
% R
% Ser:
8
8
22
22
15
8
0
8
0
8
15
29
8
8
0
% S
% Thr:
8
15
0
0
0
0
15
29
22
15
0
15
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
8
29
29
15
0
0
8
0
8
22
22
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _