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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSC
All Species:
23.03
Human Site:
T73
Identified Species:
38.97
UniProt:
P53634
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53634
NP_001805.3
463
51842
T73
V
Y
L
Q
K
L
D
T
A
Y
D
D
L
G
N
Chimpanzee
Pan troglodytes
XP_508684
463
51907
T73
V
Y
L
Q
K
L
D
T
A
Y
D
D
L
G
N
Rhesus Macaque
Macaca mulatta
XP_001104734
463
51874
T73
V
H
L
Q
K
L
D
T
A
Y
D
D
L
G
N
Dog
Lupus familis
XP_535784
481
54085
T94
V
H
L
E
K
L
D
T
A
Y
D
N
F
G
N
Cat
Felis silvestris
Mouse
Mus musculus
P97821
462
52358
T73
V
H
L
K
K
L
D
T
A
Y
D
E
L
G
N
Rat
Rattus norvegicus
P80067
462
52217
T73
I
H
L
K
K
L
D
T
A
Y
D
E
V
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512140
469
52438
H79
L
Q
K
L
D
V
A
H
D
E
L
G
N
S
G
Chicken
Gallus gallus
P43233
340
37569
Frog
Xenopus laevis
NP_001080511
458
51565
D74
K
E
L
N
I
A
E
D
Q
N
G
N
L
G
S
Zebra Danio
Brachydanio rerio
NP_999887
455
50596
H74
V
A
V
D
D
L
G
H
T
G
F
F
T
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P43510
379
42386
Sea Urchin
Strong. purpuratus
XP_001201161
459
51309
T76
A
V
D
V
Q
Y
G
T
K
G
F
W
T
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q10717
360
39181
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H166
358
38941
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.6
79
N.A.
77.7
78.6
N.A.
72
22.8
62.4
63.2
N.A.
N.A.
N.A.
23.3
54.8
Protein Similarity:
100
99.7
97.4
85.4
N.A.
86.6
87
N.A.
83.5
38
77.3
77.1
N.A.
N.A.
N.A.
38.2
71.4
P-Site Identity:
100
100
93.3
73.3
N.A.
80
66.6
N.A.
0
0
20
13.3
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
13.3
0
40
20
N.A.
N.A.
N.A.
0
13.3
Percent
Protein Identity:
N.A.
27.8
N.A.
27
N.A.
N.A.
Protein Similarity:
N.A.
42.5
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
8
0
43
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
15
0
43
8
8
0
43
22
0
0
0
% D
% Glu:
0
8
0
8
0
0
8
0
0
8
0
15
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
15
8
8
0
0
% F
% Gly:
0
0
0
0
0
0
15
0
0
15
8
8
0
50
8
% G
% His:
0
29
0
0
0
0
0
15
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
15
% I
% Lys:
8
0
8
15
43
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
8
0
50
8
0
50
0
0
0
0
8
0
36
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
8
0
15
8
0
43
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
22
8
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% S
% Thr:
0
0
0
0
0
0
0
50
8
0
0
0
15
0
0
% T
% Val:
43
8
8
8
0
8
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
15
0
0
0
8
0
0
0
43
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _