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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSC
All Species:
16.06
Human Site:
Y163
Identified Species:
27.18
UniProt:
P53634
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53634
NP_001805.3
463
51842
Y163
L
K
N
S
Q
E
K
Y
S
N
R
L
Y
K
Y
Chimpanzee
Pan troglodytes
XP_508684
463
51907
Y163
L
K
N
S
Q
E
K
Y
S
N
R
L
Y
K
Y
Rhesus Macaque
Macaca mulatta
XP_001104734
463
51874
Y163
L
K
N
S
Q
E
K
Y
S
N
R
L
Y
K
Y
Dog
Lupus familis
XP_535784
481
54085
N184
I
E
R
L
Q
E
N
N
S
N
R
L
Y
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
P97821
462
52358
Y163
L
G
G
L
Q
E
R
Y
S
E
R
L
Y
T
H
Rat
Rattus norvegicus
P80067
462
52217
Y163
L
G
G
L
Q
E
K
Y
S
E
R
L
Y
S
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512140
469
52438
L169
P
R
L
P
E
D
R
L
P
K
K
L
Y
Q
N
Chicken
Gallus gallus
P43233
340
37569
D51
G
H
N
F
H
N
T
D
M
S
Y
V
K
K
L
Frog
Xenopus laevis
NP_001080511
458
51565
Y164
E
M
L
T
S
R
V
Y
N
Y
N
H
D
F
V
Zebra Danio
Brachydanio rerio
NP_999887
455
50596
N164
M
K
L
P
Y
T
N
N
M
M
F
V
D
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P43510
379
42386
K90
N
H
V
R
L
S
V
K
G
K
Q
H
L
S
K
Sea Urchin
Strong. purpuratus
XP_001201161
459
51309
N166
F
S
Q
M
M
Y
R
N
D
K
K
M
V
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q10717
360
39181
E71
V
R
Y
G
K
S
Y
E
S
A
A
E
V
H
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H166
358
38941
K69
F
T
H
R
Y
G
K
K
Y
Q
N
V
E
E
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.6
79
N.A.
77.7
78.6
N.A.
72
22.8
62.4
63.2
N.A.
N.A.
N.A.
23.3
54.8
Protein Similarity:
100
99.7
97.4
85.4
N.A.
86.6
87
N.A.
83.5
38
77.3
77.1
N.A.
N.A.
N.A.
38.2
71.4
P-Site Identity:
100
100
100
60
N.A.
53.3
60
N.A.
13.3
13.3
6.6
6.6
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
100
73.3
N.A.
66.6
66.6
N.A.
53.3
26.6
20
26.6
N.A.
N.A.
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
27.8
N.A.
27
N.A.
N.A.
Protein Similarity:
N.A.
42.5
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
8
8
0
0
0
15
0
0
% D
% Glu:
8
8
0
0
8
43
0
8
0
15
0
8
8
22
0
% E
% Phe:
15
0
0
8
0
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
8
15
15
8
0
8
0
0
8
0
0
0
0
0
0
% G
% His:
0
15
8
0
8
0
0
0
0
0
0
15
0
8
15
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
29
0
0
8
0
36
15
0
22
15
0
8
36
22
% K
% Leu:
36
0
22
22
8
0
0
8
0
0
0
50
8
0
8
% L
% Met:
8
8
0
8
8
0
0
0
15
8
0
8
0
0
8
% M
% Asn:
8
0
29
0
0
8
15
22
8
29
15
0
0
0
8
% N
% Pro:
8
0
0
15
0
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
43
0
0
0
0
8
8
0
0
8
0
% Q
% Arg:
0
15
8
15
0
8
22
0
0
0
43
0
0
0
0
% R
% Ser:
0
8
0
22
8
15
0
0
50
8
0
0
0
15
0
% S
% Thr:
0
8
0
8
0
8
8
0
0
0
0
0
0
8
0
% T
% Val:
8
0
8
0
0
0
15
0
0
0
0
22
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
15
8
8
43
8
8
8
0
50
0
29
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _