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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSC
All Species:
25.15
Human Site:
Y193
Identified Species:
42.56
UniProt:
P53634
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53634
NP_001805.3
463
51842
Y193
T
A
T
T
Y
M
E
Y
E
T
L
T
L
G
D
Chimpanzee
Pan troglodytes
XP_508684
463
51907
Y193
T
A
T
T
Y
M
E
Y
E
T
L
T
L
G
D
Rhesus Macaque
Macaca mulatta
XP_001104734
463
51874
Y193
T
A
T
T
Y
M
E
Y
E
T
L
T
L
G
D
Dog
Lupus familis
XP_535784
481
54085
Y214
T
A
T
R
Y
I
E
Y
E
T
L
T
L
R
D
Cat
Felis silvestris
Mouse
Mus musculus
P97821
462
52358
Y193
T
A
T
A
Y
K
E
Y
E
K
M
S
L
R
D
Rat
Rattus norvegicus
P80067
462
52217
Y193
T
A
T
T
Y
E
E
Y
E
K
L
S
I
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512140
469
52438
Y199
K
A
T
T
Y
E
E
Y
E
T
L
T
L
V
E
Chicken
Gallus gallus
P43233
340
37569
P81
F
A
E
D
M
D
L
P
D
T
F
D
T
R
K
Frog
Xenopus laevis
NP_001080511
458
51565
I194
P
E
Y
E
G
M
S
I
E
D
L
V
R
R
A
Zebra Danio
Brachydanio rerio
NP_999887
455
50596
M194
E
T
L
S
I
H
E
M
L
R
R
S
G
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P43510
379
42386
S120
D
N
W
P
K
C
D
S
I
K
V
I
R
D
Q
Sea Urchin
Strong. purpuratus
XP_001201161
459
51309
D196
H
E
M
Y
T
V
E
D
M
R
R
R
A
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q10717
360
39181
R101
N
R
K
G
L
S
Y
R
L
G
I
N
R
F
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H166
358
38941
S99
S
T
N
K
K
G
L
S
Y
K
L
G
V
N
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.6
79
N.A.
77.7
78.6
N.A.
72
22.8
62.4
63.2
N.A.
N.A.
N.A.
23.3
54.8
Protein Similarity:
100
99.7
97.4
85.4
N.A.
86.6
87
N.A.
83.5
38
77.3
77.1
N.A.
N.A.
N.A.
38.2
71.4
P-Site Identity:
100
100
100
80
N.A.
60
66.6
N.A.
73.3
13.3
20
13.3
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
80
N.A.
80
20
20
26.6
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
N.A.
27.8
N.A.
27
N.A.
N.A.
Protein Similarity:
N.A.
42.5
N.A.
43.2
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
58
0
8
0
0
0
0
0
0
0
0
8
0
15
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
8
0
8
8
8
8
8
0
8
0
8
43
% D
% Glu:
8
15
8
8
0
15
65
0
58
0
0
0
0
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
0
0
0
8
8
8
0
0
0
8
0
8
8
36
8
% G
% His:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
8
8
0
8
8
8
0
0
% I
% Lys:
8
0
8
8
15
8
0
0
0
29
0
0
0
0
8
% K
% Leu:
0
0
8
0
8
0
15
0
15
0
58
0
43
0
0
% L
% Met:
0
0
8
0
8
29
0
8
8
0
8
0
0
0
0
% M
% Asn:
8
8
8
0
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% Q
% Arg:
0
8
0
8
0
0
0
8
0
15
15
8
22
36
0
% R
% Ser:
8
0
0
8
0
8
8
15
0
0
0
22
0
0
0
% S
% Thr:
43
15
50
36
8
0
0
0
0
43
0
36
8
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
8
8
8
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
8
50
0
8
50
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _