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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIMK2 All Species: 28.79
Human Site: S297 Identified Species: 63.33
UniProt: P53671 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53671 NP_005560.1 638 72232 S297 I S K S P G P S S P K E P L L
Chimpanzee Pan troglodytes XP_001148746 647 72505 G306 I D R S P G A G S L G S P A S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852696 638 72125 S297 I S K S P G P S S P K E P L L
Cat Felis silvestris
Mouse Mus musculus O54785 638 72184 S297 I S K S P G P S S P K E P L L
Rat Rattus norvegicus P53670 638 72183 S297 I S K S P G P S S P K E P L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506118 617 69519 S276 I S K S P G P S S P K E P L L
Chicken Gallus gallus P53666 642 72449 S297 I S K S P G P S S P K E P L L
Frog Xenopus laevis O42565 615 69775 S281 I D R S P G S S C V G S P S C
Zebra Danio Brachydanio rerio NP_001002651 651 74058 S303 I C K S P V S S S P K D H L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IR79 1257 139286 A340 A S T T I P P A A G A T A M T
Honey Bee Apis mellifera XP_396603 1027 115500 T299 G S S P T N L T C D L S R T R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.4 N.A. 95.4 N.A. 93 92.9 N.A. 86 85.9 52.8 65.7 N.A. 24.9 29.7 N.A. N.A.
Protein Similarity: 100 70.6 N.A. 97.6 N.A. 96 96 N.A. 91.5 91.2 68.9 77.1 N.A. 34.2 41.8 N.A. N.A.
P-Site Identity: 100 40 N.A. 100 N.A. 100 100 N.A. 100 100 40 60 N.A. 13.3 6.6 N.A. N.A.
P-Site Similarity: 100 46.6 N.A. 100 N.A. 100 100 N.A. 100 100 46.6 73.3 N.A. 40 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 10 10 10 0 10 0 10 10 0 % A
% Cys: 0 10 0 0 0 0 0 0 19 0 0 0 0 0 10 % C
% Asp: 0 19 0 0 0 0 0 0 0 10 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 55 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 73 0 10 0 10 19 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 82 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 64 0 0 0 0 0 0 0 64 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 0 10 10 0 0 64 55 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 82 10 64 0 0 64 0 0 73 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 19 0 0 0 0 0 0 0 0 0 10 0 10 % R
% Ser: 0 73 10 82 0 0 19 73 73 0 0 28 0 10 10 % S
% Thr: 0 0 10 10 10 0 0 10 0 0 0 10 0 10 10 % T
% Val: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _