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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRYBA2
All Species:
24.24
Human Site:
Y127
Identified Species:
59.26
UniProt:
P53672
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53672
NP_005200.1
197
22096
Y127
K
F
D
L
V
D
D
Y
P
S
L
P
S
M
G
Chimpanzee
Pan troglodytes
XP_001159761
149
16409
A80
G
D
Y
P
R
W
S
A
W
S
G
S
S
S
H
Rhesus Macaque
Macaca mulatta
A3RLD8
174
20712
L105
H
K
G
L
M
M
E
L
S
E
D
C
P
S
I
Dog
Lupus familis
XP_545651
392
43497
Y322
K
F
E
L
S
D
D
Y
P
S
L
P
S
M
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJV1
197
22218
Y127
K
F
E
L
S
D
D
Y
P
S
L
P
S
M
G
Rat
Rattus norvegicus
P14881
215
25252
Y145
Q
W
E
I
C
D
D
Y
P
S
L
Q
A
M
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510489
218
25032
Y148
Q
W
E
L
C
D
D
Y
P
S
L
Q
A
M
G
Chicken
Gallus gallus
P55164
196
22985
Y126
K
F
E
L
S
D
D
Y
P
S
L
Q
A
M
G
Frog
Xenopus laevis
NP_001088424
196
23224
Y126
K
F
E
I
C
D
D
Y
P
S
L
Q
A
M
G
Zebra Danio
Brachydanio rerio
Q5XTN8
183
21493
D114
G
Q
C
V
E
L
C
D
D
C
P
F
L
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.6
30.9
45.9
N.A.
90.8
49.7
N.A.
42.6
62.9
64.9
40
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
74.6
52.2
47.4
N.A.
93.4
67.9
N.A.
59.6
78.6
79.1
58.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
86.6
N.A.
86.6
53.3
N.A.
60
73.3
66.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
20
93.3
N.A.
93.3
86.6
N.A.
86.6
86.6
86.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
40
0
0
% A
% Cys:
0
0
10
0
30
0
10
0
0
10
0
10
0
0
0
% C
% Asp:
0
10
10
0
0
70
70
10
10
0
10
0
0
0
0
% D
% Glu:
0
0
60
0
10
0
10
0
0
10
0
0
0
0
0
% E
% Phe:
0
50
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
20
0
10
0
0
0
0
0
0
0
10
0
0
0
70
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
50
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
60
0
10
0
10
0
0
70
0
10
0
0
% L
% Met:
0
0
0
0
10
10
0
0
0
0
0
0
0
70
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
70
0
10
30
10
0
0
% P
% Gln:
20
10
0
0
0
0
0
0
0
0
0
40
0
10
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
30
0
10
0
10
80
0
10
40
20
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
20
0
0
0
10
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _