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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRYBA4
All Species:
29.7
Human Site:
Y126
Identified Species:
72.59
UniProt:
P53673
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53673
NP_001877.1
196
22374
Y126
K
G
E
L
S
D
D
Y
P
S
L
Q
A
M
G
Chimpanzee
Pan troglodytes
XP_525555
196
22383
Y126
K
G
E
L
S
D
D
Y
P
S
L
Q
A
M
G
Rhesus Macaque
Macaca mulatta
A3RLD7
175
20906
L106
L
R
G
Q
M
S
E
L
T
D
D
C
L
S
V
Dog
Lupus familis
XP_545651
392
43497
Y322
K
F
E
L
S
D
D
Y
P
S
L
P
S
M
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJV0
196
22450
Y126
K
G
E
L
N
D
D
Y
P
S
L
Q
A
M
G
Rat
Rattus norvegicus
P56374
196
22363
Y126
K
G
E
L
S
D
D
Y
P
S
L
Q
A
M
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510489
218
25032
Y148
Q
W
E
L
C
D
D
Y
P
S
L
Q
A
M
G
Chicken
Gallus gallus
P10042
215
24730
Y145
Q
W
E
I
S
D
D
Y
P
S
L
Q
A
M
G
Frog
Xenopus laevis
NP_001080829
214
25237
Y144
K
W
D
M
C
D
D
Y
P
S
L
Q
A
M
G
Zebra Danio
Brachydanio rerio
Q5XTN8
183
21493
D114
G
Q
C
V
E
L
C
D
D
C
P
F
L
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
33.6
29.3
N.A.
91.8
91.8
N.A.
50.9
59.5
58.4
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
52
37.7
N.A.
96.4
96.4
N.A.
64.6
73.9
75.6
56.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
80
N.A.
93.3
100
N.A.
80
80
73.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
86.6
N.A.
100
100
N.A.
86.6
93.3
86.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% A
% Cys:
0
0
10
0
20
0
10
0
0
10
0
10
0
0
0
% C
% Asp:
0
0
10
0
0
80
80
10
10
10
10
0
0
0
0
% D
% Glu:
0
0
70
0
10
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
40
10
0
0
0
0
0
0
0
0
0
0
0
80
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
60
0
10
0
10
0
0
80
0
20
0
0
% L
% Met:
0
0
0
10
10
0
0
0
0
0
0
0
0
80
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
80
0
10
10
0
0
0
% P
% Gln:
20
10
0
10
0
0
0
0
0
0
0
70
0
10
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
50
10
0
0
0
80
0
0
10
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _