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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRYBB1
All Species:
11.82
Human Site:
S77
Identified Species:
28.89
UniProt:
P53674
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53674
NP_001878.1
252
28023
S77
Q
G
R
R
A
E
F
S
G
E
C
S
N
L
A
Chimpanzee
Pan troglodytes
XP_515047
252
28019
S77
Q
G
R
R
A
E
F
S
G
E
C
S
N
L
A
Rhesus Macaque
Macaca mulatta
NP_001116372
211
24097
E44
K
H
C
E
L
S
A
E
C
P
S
L
T
D
S
Dog
Lupus familis
XP_543459
248
27747
N78
E
F
S
G
E
C
L
N
L
G
D
R
G
F
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVJ5
250
27984
S75
Q
G
R
R
V
E
F
S
G
E
C
L
N
L
G
Rat
Rattus norvegicus
P02523
250
28074
S75
Q
G
R
R
V
E
F
S
G
E
C
L
N
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509294
205
23392
C38
S
H
E
L
S
G
P
C
S
N
L
K
E
T
G
Chicken
Gallus gallus
P07530
238
27249
A71
T
S
E
C
L
N
L
A
D
C
G
F
D
R
V
Frog
Xenopus laevis
Q91724
175
21633
E8
M
E
R
I
F
F
Y
E
D
R
N
F
Q
G
R
Zebra Danio
Brachydanio rerio
Q5XTN8
183
21493
C15
I
V
F
F
E
G
K
C
F
T
G
R
R
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
45.2
82.9
N.A.
80.1
80.9
N.A.
47.2
63.4
27.3
31.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
61.5
88.8
N.A.
87.6
87.6
N.A.
60.3
76.1
43.2
47.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
80
80
N.A.
0
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
13.3
N.A.
80
80
N.A.
6.6
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
0
10
10
0
0
0
0
0
0
20
% A
% Cys:
0
0
10
10
0
10
0
20
10
10
40
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
20
0
10
0
10
10
10
% D
% Glu:
10
10
20
10
20
40
0
20
0
40
0
0
10
0
10
% E
% Phe:
0
10
10
10
10
10
40
0
10
0
0
20
0
10
0
% F
% Gly:
0
40
0
10
0
20
0
0
40
10
20
0
10
10
30
% G
% His:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% K
% Leu:
0
0
0
10
20
0
20
0
10
0
10
30
0
50
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
10
10
0
40
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% P
% Gln:
40
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
50
40
0
0
0
0
0
10
0
20
10
10
10
% R
% Ser:
10
10
10
0
10
10
0
40
10
0
10
20
0
0
10
% S
% Thr:
10
0
0
0
0
0
0
0
0
10
0
0
10
10
0
% T
% Val:
0
10
0
0
20
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _