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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP3M2 All Species: 24.55
Human Site: S365 Identified Species: 38.57
UniProt: P53677 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53677 NP_001127768.1 418 46977 S365 M S L Q A G A S K P D E N P T
Chimpanzee Pan troglodytes XP_001141331 436 49226 S365 M S L Q A G A S K P D E N P T
Rhesus Macaque Macaca mulatta XP_001098843 418 46925 P365 V N L Q S G A P K P E E N P S
Dog Lupus familis XP_539956 418 46980 S365 M S L Q A G A S K P D E N P T
Cat Felis silvestris
Mouse Mus musculus Q8R2R9 418 46898 S365 M G L Q V G A S K P D E N P T
Rat Rattus norvegicus P53678 418 46856 S365 M G L Q V G A S K P D E N P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509676 418 46941 S365 M S L Q A G A S K P D E N P T
Chicken Gallus gallus Q5ZMP7 418 46954 P365 V N L Q S G A P K P E E N P S
Frog Xenopus laevis Q801Q8 435 49666 K380 L P T N D K K K W A R P P I S
Zebra Danio Brachydanio rerio Q6NWK2 436 49641 K381 L P T N D K K K W A R P P I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788873 415 46777 N363 S I T P G T T N I D A N P S V
Honey Bee Apis mellifera XP_624899 417 47249 T365 T V Q N S A S T M E S N P A I
Nematode Worm Caenorhab. elegans P35602 422 48210 S366 L S L P S V M S E E S E G R P
Sea Urchin Strong. purpuratus XP_788000 416 46931 P363 M S L Q S G V P P P E A N P T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q00776 475 53855 F364 D D A D T P T F K Y S H G S L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 83.9 99.5 N.A. 98.3 98.3 N.A. 98.8 83 26.2 26.1 N.A. 69.8 72 27.2 77.5
Protein Similarity: 100 95.8 94.5 99.5 N.A. 99.2 99.2 N.A. 99.2 93.7 47.8 47.4 N.A. 85.6 86.8 50.4 89.9
P-Site Identity: 100 100 60 100 N.A. 86.6 86.6 N.A. 100 60 0 0 N.A. 0 0 26.6 60
P-Site Similarity: 100 100 93.3 100 N.A. 86.6 86.6 N.A. 100 93.3 13.3 13.3 N.A. 6.6 20 46.6 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 27 7 54 0 0 14 7 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 0 7 14 0 0 0 0 7 40 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 7 14 20 60 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 0 14 0 0 7 60 0 0 0 0 0 0 14 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 7 0 0 0 0 14 7 % I
% Lys: 0 0 0 0 0 14 14 14 60 0 0 0 0 0 0 % K
% Leu: 20 0 67 0 0 0 0 0 0 0 0 0 0 0 7 % L
% Met: 47 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % M
% Asn: 0 14 0 20 0 0 0 7 0 0 0 14 60 0 0 % N
% Pro: 0 14 0 14 0 7 0 20 7 60 0 14 27 60 7 % P
% Gln: 0 0 7 60 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 14 0 0 7 0 % R
% Ser: 7 40 0 0 34 0 7 47 0 0 20 0 0 14 27 % S
% Thr: 7 0 20 0 7 7 14 7 0 0 0 0 0 0 47 % T
% Val: 14 7 0 0 14 7 7 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 14 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _