KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3M2
All Species:
26.67
Human Site:
T300
Identified Species:
41.9
UniProt:
P53677
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53677
NP_001127768.1
418
46977
T300
I
T
V
G
P
K
Q
T
M
G
K
T
I
E
G
Chimpanzee
Pan troglodytes
XP_001141331
436
49226
T300
I
T
V
G
P
K
Q
T
M
G
K
T
I
E
G
Rhesus Macaque
Macaca mulatta
XP_001098843
418
46925
N300
I
T
I
G
P
K
Q
N
M
G
K
T
I
E
G
Dog
Lupus familis
XP_539956
418
46980
T300
I
T
V
G
P
K
Q
T
M
G
K
T
I
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2R9
418
46898
T300
I
T
V
G
P
K
Q
T
M
G
K
T
I
E
G
Rat
Rattus norvegicus
P53678
418
46856
T300
I
T
V
G
P
K
Q
T
M
G
K
T
I
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509676
418
46941
T300
I
T
V
G
P
K
Q
T
M
G
K
T
I
E
G
Chicken
Gallus gallus
Q5ZMP7
418
46954
N300
V
T
I
G
P
K
Q
N
M
G
K
T
V
E
G
Frog
Xenopus laevis
Q801Q8
435
49666
L315
K
S
N
F
K
P
S
L
L
A
Q
K
I
E
V
Zebra Danio
Brachydanio rerio
Q6NWK2
436
49641
L316
K
S
N
F
K
P
S
L
L
A
Q
K
I
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788873
415
46777
L298
T
I
G
P
R
N
T
L
G
R
T
V
D
K
V
Honey Bee
Apis mellifera
XP_624899
417
47249
I300
T
V
G
P
K
Q
T
I
G
R
T
V
E
N
V
Nematode Worm
Caenorhab. elegans
P35602
422
48210
K301
I
K
A
K
S
Q
F
K
R
R
S
T
A
N
N
Sea Urchin
Strong. purpuratus
XP_788000
416
46931
T298
V
M
V
G
P
K
Q
T
M
G
K
T
V
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
G299
I
T
F
I
P
P
D
G
K
F
D
L
M
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
83.9
99.5
N.A.
98.3
98.3
N.A.
98.8
83
26.2
26.1
N.A.
69.8
72
27.2
77.5
Protein Similarity:
100
95.8
94.5
99.5
N.A.
99.2
99.2
N.A.
99.2
93.7
47.8
47.4
N.A.
85.6
86.8
50.4
89.9
P-Site Identity:
100
100
86.6
100
N.A.
100
100
N.A.
100
73.3
13.3
13.3
N.A.
0
0
13.3
73.3
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
100
93.3
33.3
33.3
N.A.
6.6
6.6
20
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
0
0
0
0
14
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
0
7
0
7
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
7
74
0
% E
% Phe:
0
0
7
14
0
0
7
0
0
7
0
0
0
0
0
% F
% Gly:
0
0
14
60
0
0
0
7
14
60
0
0
0
0
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
60
7
14
7
0
0
0
7
0
0
0
0
60
0
0
% I
% Lys:
14
7
0
7
20
60
0
7
7
0
60
14
0
7
0
% K
% Leu:
0
0
0
0
0
0
0
20
14
0
0
7
0
0
0
% L
% Met:
0
7
0
0
0
0
0
0
60
0
0
0
7
0
0
% M
% Asn:
0
0
14
0
0
7
0
14
0
0
0
0
0
20
14
% N
% Pro:
0
0
0
14
67
20
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
14
60
0
0
0
14
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
7
20
0
0
0
0
0
% R
% Ser:
0
14
0
0
7
0
14
0
0
0
7
0
0
0
0
% S
% Thr:
14
60
0
0
0
0
14
47
0
0
14
67
0
0
0
% T
% Val:
14
7
47
0
0
0
0
0
0
0
0
14
14
0
27
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _