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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3M2
All Species:
22.73
Human Site:
T40
Identified Species:
35.71
UniProt:
P53677
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53677
NP_001127768.1
418
46977
T40
F
E
A
Q
E
R
A
T
E
A
E
N
V
P
P
Chimpanzee
Pan troglodytes
XP_001141331
436
49226
T40
F
E
A
Q
E
R
A
T
E
A
E
N
V
P
P
Rhesus Macaque
Macaca mulatta
XP_001098843
418
46925
A40
F
E
A
Q
E
K
A
A
D
V
E
N
V
P
P
Dog
Lupus familis
XP_539956
418
46980
T40
F
E
A
Q
E
R
A
T
E
A
E
N
V
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2R9
418
46898
T40
F
E
A
Q
E
R
A
T
E
A
E
N
V
P
P
Rat
Rattus norvegicus
P53678
418
46856
T40
F
E
A
Q
E
R
A
T
E
A
E
N
V
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509676
418
46941
T40
F
E
A
Q
E
R
A
T
E
A
E
N
V
P
P
Chicken
Gallus gallus
Q5ZMP7
418
46954
I40
F
E
A
Q
E
K
A
I
D
V
E
N
V
P
P
Frog
Xenopus laevis
Q801Q8
435
49666
R40
R
V
N
V
I
H
A
R
Q
Q
V
R
S
P
V
Zebra Danio
Brachydanio rerio
Q6NWK2
436
49641
R40
R
V
N
V
I
H
A
R
Q
Q
V
R
S
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788873
415
46777
P40
L
D
A
Q
R
A
A
P
Y
D
V
P
P
V
I
Honey Bee
Apis mellifera
XP_624899
417
47249
L40
F
D
Q
Q
R
R
V
L
S
P
E
D
T
P
P
Nematode Worm
Caenorhab. elegans
P35602
422
48210
E41
I
H
L
L
M
E
K
E
E
E
G
S
A
A
P
Sea Urchin
Strong. purpuratus
XP_788000
416
46931
C40
F
E
A
Q
E
K
A
C
S
K
L
D
V
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
E40
P
I
L
L
S
D
L
E
E
Q
S
N
L
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
83.9
99.5
N.A.
98.3
98.3
N.A.
98.8
83
26.2
26.1
N.A.
69.8
72
27.2
77.5
Protein Similarity:
100
95.8
94.5
99.5
N.A.
99.2
99.2
N.A.
99.2
93.7
47.8
47.4
N.A.
85.6
86.8
50.4
89.9
P-Site Identity:
100
100
73.3
100
N.A.
100
100
N.A.
100
73.3
13.3
13.3
N.A.
20
40
13.3
60
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
100
86.6
20
20
N.A.
26.6
53.3
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
67
0
0
7
80
7
0
40
0
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
14
0
0
0
7
0
0
14
7
0
14
0
0
0
% D
% Glu:
0
60
0
0
60
7
0
14
54
7
60
0
0
0
0
% E
% Phe:
67
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
7
0
0
0
14
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
7
0
0
14
0
0
7
0
0
0
0
0
7
7
% I
% Lys:
0
0
0
0
0
20
7
0
0
7
0
0
0
0
0
% K
% Leu:
7
0
14
14
0
0
7
7
0
0
7
0
7
0
0
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
14
0
0
0
0
0
0
0
0
60
0
0
0
% N
% Pro:
7
0
0
0
0
0
0
7
0
7
0
7
7
80
80
% P
% Gln:
0
0
7
74
0
0
0
0
14
20
0
0
0
0
0
% Q
% Arg:
14
0
0
0
14
47
0
14
0
0
0
14
0
0
0
% R
% Ser:
0
0
0
0
7
0
0
0
14
0
7
7
14
0
0
% S
% Thr:
0
0
0
0
0
0
0
40
0
0
0
0
7
0
0
% T
% Val:
0
14
0
14
0
0
7
0
0
14
20
0
60
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _