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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3M2
All Species:
40.91
Human Site:
Y180
Identified Species:
64.29
UniProt:
P53677
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53677
NP_001127768.1
418
46977
Y180
K
Y
T
N
N
E
A
Y
F
D
V
I
E
E
I
Chimpanzee
Pan troglodytes
XP_001141331
436
49226
Y180
K
Y
T
N
N
E
A
Y
F
D
V
I
E
E
I
Rhesus Macaque
Macaca mulatta
XP_001098843
418
46925
Y180
K
Y
T
N
N
E
A
Y
F
D
V
V
E
E
I
Dog
Lupus familis
XP_539956
418
46980
Y180
K
Y
T
N
N
E
A
Y
F
D
V
I
E
E
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2R9
418
46898
Y180
K
Y
T
N
N
E
A
Y
F
D
V
V
E
E
I
Rat
Rattus norvegicus
P53678
418
46856
Y180
K
Y
T
N
N
E
A
Y
F
D
V
V
E
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509676
418
46941
Y180
K
Y
T
N
N
E
A
Y
F
D
V
I
E
E
I
Chicken
Gallus gallus
Q5ZMP7
418
46954
Y180
K
Y
T
N
N
E
A
Y
F
D
V
I
E
E
I
Frog
Xenopus laevis
Q801Q8
435
49666
H195
Q
G
Q
V
L
S
A
H
V
S
G
R
V
V
M
Zebra Danio
Brachydanio rerio
Q6NWK2
436
49641
V196
G
Q
V
L
S
A
H
V
S
G
R
V
V
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788873
415
46777
Y178
R
Y
T
N
N
E
A
Y
F
D
V
I
E
E
V
Honey Bee
Apis mellifera
XP_624899
417
47249
Y180
K
Y
T
N
N
E
A
Y
F
D
V
V
E
E
V
Nematode Worm
Caenorhab. elegans
P35602
422
48210
L181
V
I
E
S
V
N
M
L
A
S
A
N
G
T
V
Sea Urchin
Strong. purpuratus
XP_788000
416
46931
E178
G
V
K
Y
T
N
N
E
A
Y
F
D
V
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
F179
T
H
K
K
N
E
A
F
L
D
I
V
E
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
83.9
99.5
N.A.
98.3
98.3
N.A.
98.8
83
26.2
26.1
N.A.
69.8
72
27.2
77.5
Protein Similarity:
100
95.8
94.5
99.5
N.A.
99.2
99.2
N.A.
99.2
93.7
47.8
47.4
N.A.
85.6
86.8
50.4
89.9
P-Site Identity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
100
100
6.6
0
N.A.
86.6
86.6
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
26.6
13.3
N.A.
100
100
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
80
0
14
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
74
0
7
0
0
0
% D
% Glu:
0
0
7
0
0
74
0
7
0
0
0
0
74
67
7
% E
% Phe:
0
0
0
0
0
0
0
7
67
0
7
0
0
0
0
% F
% Gly:
14
7
0
0
0
0
0
0
0
7
7
0
7
0
0
% G
% His:
0
7
0
0
0
0
7
7
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
7
40
0
7
60
% I
% Lys:
60
0
14
7
0
0
0
0
0
0
0
0
0
0
7
% K
% Leu:
0
0
0
7
7
0
0
7
7
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
7
0
0
0
0
0
0
7
7
% M
% Asn:
0
0
0
67
74
14
7
0
0
0
0
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% R
% Ser:
0
0
0
7
7
7
0
0
7
14
0
0
0
7
0
% S
% Thr:
7
0
67
0
7
0
0
0
0
0
0
0
0
7
0
% T
% Val:
7
7
7
7
7
0
0
7
7
0
67
40
20
7
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
67
0
7
0
0
0
67
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _