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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3M2
All Species:
45.45
Human Site:
Y262
Identified Species:
71.43
UniProt:
P53677
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53677
NP_001127768.1
418
46977
Y262
G
N
F
R
L
L
S
Y
H
V
S
A
Q
N
L
Chimpanzee
Pan troglodytes
XP_001141331
436
49226
Y262
G
N
F
R
L
L
S
Y
H
V
S
A
Q
N
L
Rhesus Macaque
Macaca mulatta
XP_001098843
418
46925
Y262
G
N
F
R
L
I
S
Y
R
V
S
S
Q
N
L
Dog
Lupus familis
XP_539956
418
46980
Y262
G
N
F
R
L
L
S
Y
H
V
S
A
Q
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2R9
418
46898
Y262
G
N
F
R
L
L
A
Y
H
V
S
A
Q
N
L
Rat
Rattus norvegicus
P53678
418
46856
Y262
G
N
F
R
L
L
S
Y
H
V
S
A
Q
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509676
418
46941
Y262
G
N
F
R
L
L
S
Y
H
V
S
A
Q
N
L
Chicken
Gallus gallus
Q5ZMP7
418
46954
Y262
G
N
F
R
L
I
S
Y
R
V
S
S
Q
N
L
Frog
Xenopus laevis
Q801Q8
435
49666
Y277
G
E
Y
E
L
M
R
Y
R
T
T
K
D
I
I
Zebra Danio
Brachydanio rerio
Q6NWK2
436
49641
Y278
G
E
Y
E
L
M
R
Y
R
T
T
K
D
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788873
415
46777
Y260
G
N
F
R
L
M
S
Y
H
I
S
S
Q
S
V
Honey Bee
Apis mellifera
XP_624899
417
47249
Y262
G
N
F
R
L
L
S
Y
H
I
G
S
Q
S
I
Nematode Worm
Caenorhab. elegans
P35602
422
48210
L263
P
P
D
G
A
F
E
L
M
S
Y
R
L
T
T
Sea Urchin
Strong. purpuratus
XP_788000
416
46931
L260
P
D
G
N
F
R
L
L
S
Y
H
I
G
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
S261
K
P
S
I
T
S
S
S
A
T
N
K
K
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
83.9
99.5
N.A.
98.3
98.3
N.A.
98.8
83
26.2
26.1
N.A.
69.8
72
27.2
77.5
Protein Similarity:
100
95.8
94.5
99.5
N.A.
99.2
99.2
N.A.
99.2
93.7
47.8
47.4
N.A.
85.6
86.8
50.4
89.9
P-Site Identity:
100
100
80
100
N.A.
93.3
100
N.A.
100
80
20
20
N.A.
66.6
66.6
0
0
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
100
93.3
46.6
46.6
N.A.
100
93.3
0
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
7
0
7
0
0
40
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
0
0
0
0
0
0
0
0
14
0
0
% D
% Glu:
0
14
0
14
0
0
7
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
67
0
7
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
80
0
7
7
0
0
0
0
0
0
7
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
54
0
7
0
0
0
0
% H
% Ile:
0
0
0
7
0
14
0
0
0
14
0
7
0
14
20
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
20
7
7
0
% K
% Leu:
0
0
0
0
80
47
7
14
0
0
0
0
7
0
54
% L
% Met:
0
0
0
0
0
20
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
67
0
7
0
0
0
0
0
0
7
0
0
54
0
% N
% Pro:
14
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% Q
% Arg:
0
0
0
67
0
7
14
0
27
0
0
7
0
0
0
% R
% Ser:
0
0
7
0
0
7
67
7
7
7
60
27
0
14
7
% S
% Thr:
0
0
0
0
7
0
0
0
0
20
14
0
0
7
7
% T
% Val:
0
0
0
0
0
0
0
0
0
54
0
0
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
14
0
0
0
0
80
0
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _