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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3M2
All Species:
33.03
Human Site:
Y399
Identified Species:
51.9
UniProt:
P53677
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53677
NP_001127768.1
418
46977
Y399
L
D
M
Y
G
E
K
Y
K
P
F
K
G
I
K
Chimpanzee
Pan troglodytes
XP_001141331
436
49226
H399
L
L
F
L
F
W
N
H
W
A
F
P
G
L
K
Rhesus Macaque
Macaca mulatta
XP_001098843
418
46925
Y399
L
D
M
Y
G
E
K
Y
K
P
F
K
G
V
K
Dog
Lupus familis
XP_539956
418
46980
Y399
L
D
M
Y
G
E
K
Y
K
P
F
K
G
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2R9
418
46898
Y399
L
D
M
Y
G
E
K
Y
K
P
F
K
G
I
K
Rat
Rattus norvegicus
P53678
418
46856
Y399
L
D
M
Y
G
E
K
Y
K
P
F
K
G
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509676
418
46941
Y399
L
D
M
Y
G
E
K
Y
K
P
F
K
G
I
K
Chicken
Gallus gallus
Q5ZMP7
418
46954
Y399
L
D
M
Y
G
E
K
Y
K
P
F
K
G
V
K
Frog
Xenopus laevis
Q801Q8
435
49666
S414
F
E
P
K
L
N
Y
S
D
H
D
V
I
K
W
Zebra Danio
Brachydanio rerio
Q6NWK2
436
49641
S415
F
E
S
K
L
N
Y
S
D
H
D
V
I
K
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788873
415
46777
K397
D
M
Y
G
E
K
Y
K
P
F
K
G
V
K
Y
Honey Bee
Apis mellifera
XP_624899
417
47249
K399
D
M
Y
G
E
K
Y
K
P
F
K
G
V
K
Y
Nematode Worm
Caenorhab. elegans
P35602
422
48210
S400
Y
L
K
I
I
E
K
S
G
Y
Q
A
L
P
W
Sea Urchin
Strong. purpuratus
XP_788000
416
46931
Y397
L
D
M
Y
G
E
K
Y
K
P
F
K
G
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
E398
K
E
Y
S
M
S
A
E
L
G
L
P
S
I
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
83.9
99.5
N.A.
98.3
98.3
N.A.
98.8
83
26.2
26.1
N.A.
69.8
72
27.2
77.5
Protein Similarity:
100
95.8
94.5
99.5
N.A.
99.2
99.2
N.A.
99.2
93.7
47.8
47.4
N.A.
85.6
86.8
50.4
89.9
P-Site Identity:
100
26.6
93.3
100
N.A.
100
100
N.A.
100
93.3
0
0
N.A.
0
0
13.3
93.3
P-Site Similarity:
100
40
100
100
N.A.
100
100
N.A.
100
100
6.6
6.6
N.A.
6.6
6.6
13.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
0
0
7
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
14
54
0
0
0
0
0
0
14
0
14
0
0
0
0
% D
% Glu:
0
20
0
0
14
60
0
7
0
0
0
0
0
0
0
% E
% Phe:
14
0
7
0
7
0
0
0
0
14
60
0
0
0
0
% F
% Gly:
0
0
0
14
54
0
0
0
7
7
0
14
60
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
14
0
0
0
0
0
% H
% Ile:
0
0
0
7
7
0
0
0
0
0
0
0
14
40
0
% I
% Lys:
7
0
7
14
0
14
60
14
54
0
14
54
0
27
60
% K
% Leu:
60
14
0
7
14
0
0
0
7
0
7
0
7
7
0
% L
% Met:
0
14
54
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
14
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
0
0
0
14
54
0
14
0
7
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
7
0
7
0
20
0
0
0
0
7
0
7
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
14
14
20
0
% V
% Trp:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
20
% W
% Tyr:
7
0
20
54
0
0
27
54
0
7
0
0
0
0
14
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _