KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP3M2
All Species:
38.48
Human Site:
Y55
Identified Species:
60.48
UniProt:
P53677
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53677
NP_001127768.1
418
46977
Y55
V
I
P
T
P
H
H
Y
L
L
S
V
Y
R
H
Chimpanzee
Pan troglodytes
XP_001141331
436
49226
Y55
V
I
P
T
P
H
H
Y
L
L
S
V
Y
R
H
Rhesus Macaque
Macaca mulatta
XP_001098843
418
46925
Y55
V
I
S
T
P
H
H
Y
L
I
S
I
Y
R
D
Dog
Lupus familis
XP_539956
418
46980
Y55
V
I
P
T
P
H
H
Y
L
L
S
V
Y
R
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2R9
418
46898
Y55
V
I
P
T
P
H
H
Y
L
L
S
V
Y
R
H
Rat
Rattus norvegicus
P53678
418
46856
Y55
V
I
P
T
P
H
H
Y
L
L
S
V
Y
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509676
418
46941
Y55
V
I
P
T
P
H
H
Y
L
L
S
V
Y
R
H
Chicken
Gallus gallus
Q5ZMP7
418
46954
Y55
V
I
S
T
P
L
H
Y
L
I
S
I
Y
R
D
Frog
Xenopus laevis
Q801Q8
435
49666
F55
T
N
I
A
R
T
S
F
F
H
V
K
R
S
N
Zebra Danio
Brachydanio rerio
Q6NWK2
436
49641
F55
T
N
I
A
R
T
S
F
F
H
V
K
R
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788873
415
46777
I55
A
T
P
H
Y
Y
L
I
T
V
Q
R
D
T
V
Honey Bee
Apis mellifera
XP_624899
417
47249
Y55
V
I
A
T
P
H
H
Y
L
I
S
I
Y
R
C
Nematode Worm
Caenorhab. elegans
P35602
422
48210
N56
V
L
T
Y
Q
D
T
N
F
V
F
I
K
H
T
Sea Urchin
Strong. purpuratus
XP_788000
416
46931
Y55
I
I
A
T
P
H
H
Y
L
I
S
I
Y
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
L55
P
C
L
N
H
N
G
L
E
Y
L
F
I
Q
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.8
83.9
99.5
N.A.
98.3
98.3
N.A.
98.8
83
26.2
26.1
N.A.
69.8
72
27.2
77.5
Protein Similarity:
100
95.8
94.5
99.5
N.A.
99.2
99.2
N.A.
99.2
93.7
47.8
47.4
N.A.
85.6
86.8
50.4
89.9
P-Site Identity:
100
100
73.3
100
N.A.
100
100
N.A.
100
66.6
0
0
N.A.
6.6
73.3
6.6
66.6
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
100
80
13.3
13.3
N.A.
20
86.6
26.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
14
14
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
0
7
0
0
0
0
0
0
7
0
14
% D
% Glu:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
14
20
0
7
7
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
7
7
60
67
0
0
14
0
0
0
7
47
% H
% Ile:
7
67
14
0
0
0
0
7
0
27
0
34
7
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
14
7
0
0
% K
% Leu:
0
7
7
0
0
7
7
7
67
40
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
14
0
7
0
7
0
7
0
0
0
0
0
0
20
% N
% Pro:
7
0
47
0
67
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
7
0
0
7
0
% Q
% Arg:
0
0
0
0
14
0
0
0
0
0
0
7
14
67
0
% R
% Ser:
0
0
14
0
0
0
14
0
0
0
67
0
0
14
0
% S
% Thr:
14
7
7
67
0
14
7
0
7
0
0
0
0
7
7
% T
% Val:
67
0
0
0
0
0
0
0
0
14
14
40
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
7
0
67
0
7
0
0
67
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _